Corrosion behaviour of the porous iron scaffold in simulated body fluid for biodegradable implant application

Sharma, Pawan; Pandey, Pulak M.

doi:10.1016/j.msec.2019.01.114

Cited by 68 publications

(64 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Temporary intervention is desirable in some specific orthopedic, cardiovascular, and pediatric applications. Biodegradable materials can avoid the negative effects associated with long-term implants, for instance, stress shielding, inflammation, thrombus formation, migration of the implant, and re-intervention to remove devices with a transient function [ 4 , 5 , 6 , 7 , 8 , 9 ]. Degradable biomaterials represent the next generation of highly bioactive materials, which are envisaged to facilitate the restoration of diseased tissue and thereafter naturally decompose in the human body environment without leaving toxic degradation products, to be replaced by healing tissue [ 2 , 6 , 10 , 11 , 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

“…Recently, network-like metal foams [ 6 , 17 , 22 , 23 ], including open-cell iron foams [ 9 , 11 , 18 ], have been identified as promising materials for hard tissue scaffolds as they exhibit a natural bone-like structure, which supports the vascularization, growth, and proliferation of bone cells and reduces corrosion resistance [ 6 , 17 , 18 , 22 , 24 ]. The improvement of the mechanical strength of iron foams can be achieved by the addition of low amounts of phosphorus without retarding the corrosion rate or affecting the cell proliferation [ 11 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Degradation Performance of Open-Cell Biomaterials from Phosphated Carbonyl Iron Powder with PEG Coating

et al. 2020

View full text Add to dashboard Cite

Advances in biomedicine and development of modern technologies in the last century have fostered the improvement in human longevity and well-being. This progress simultaneously initiated the need for novel biomaterials. Recently, degradable metallic biomaterials have attracted serious attention in scientific and clinical research owing to their utilization in some specific applications. This work investigates the effect of the polyethylene glycol (PEG) coating of open-cell iron and phosphorus/iron foams on their microstructure and corrosion properties. The addition of phosphorus causes a slight increase in pore size and the deposition of a polymer coating results in a smoothened surface and a moderate decrease in pore diameter. The PEG coating leads to an increase in corrosion rates in both foams and potentially a more desirable product.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Degradation Performance of Open-Cell Biomaterials from Phosphated Carbonyl Iron Powder with PEG Coating

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Furthermore, If α lies between 0.5 and 1, it demonstrates the heterogeneous, rough, and nonhomogeneous current distribution. [ 49,51,52 ] With the findings, it can be deduced that the higher R 2 and R 3 values with lower CPE 1 associated to the improvement in corrosion resistance. It was owing to the generation of compact corrosion products layer at the samples surface, thereby increasing the stability of the material.…”

Section: Resultsmentioning

confidence: 84%

Evaluation of in vitro corrosion behavior of zinc–hydroxyapatite and zinc–hydroxyapatite–iron as biodegradable composites

Pathak

Pandey

2020

J Biomed Mater Res

View full text Add to dashboard Cite

Zinc (Zn) based biomaterials have been emerged as one of the capable biodegradable materials for biomedical applications because of the ideal degradation properties. In the present work, corrosion kinetics of Zn–hydroxyapatite (HA), and Zn–HA–iron (Fe) materials developed using microwave sintering process were investigated. The effect of the inclusion of HA and Fe in Zn on corrosion properties have been evaluated in the simulated body fluid solution. Further, the wettability test of the developed composites was performed to confirm the hydrophilic nature of the surface of all samples. Zn‐3HA was found to have better hydrophilicity as compared to other samples. Increased corrosion rate and pH of Zn‐5HA‐2Fe samples were attributed to the addition of HA and Fe in the Zn matrix. The corrosion rate and weight loss rate from electrochemical and immersion testing of all samples were found in the order from highest to lowest: Zn‐5HA‐2Fe > Zn‐3HA > Zn‐3HA‐2Fe > Zn. The highest cell viability nearly 100% was obtained for Zn‐3HA samples, whereas other samples also showed sufficient biocompatibility to be utilized for biomedical applications.

show abstract

“…This showed the capacitive behavior of both the samples; however, the large frequency capacitive loop indicated the generation of corrosion products on the uniform corrosion area of the sample surface. 13,17 Further, the low-frequency capacitive loop was subjected to interfacial charge transfer, thus creating an electrochemical double layer at the sample and or SBF solution. Moreover, the small diameter, obtained for Zn-3HA sample, indicated the reduction in corrosion resistance as compared to pure Zn.…”

Section: Corrosion Study Of the Optimized Samplementioning

confidence: 99%

“…However, the high magnitude of elastic modulus and a slower corrosion rate confines the application of Fe-based BMs. 13 Whereas Mg and Mg-based alloys have sufficient strength, nevertheless generation of more hydrogen gas even before its dissolution or diffusion in the surrounding tissues under the physiological environment is a critical issue. This leads to cortical defects to impair the connection with the bone, and too fast degradation rate causes to lose the mechanical properties in quick time to limit its use.…”

Section: Introductionmentioning

confidence: 99%

An experimental investigation of the fabrication of biodegradable zinc–hydroxyapatite composite material using microwave sintering

Pathak

Pandey

2020

Proceedings of the Institution of Mechanical Engineers, Part C:

View full text Add to dashboard Cite

The present work focuses on the fabrication of zinc–hydroxyapatite biodegradable composite with the use of pressureless microwave sintering for the orthopedic load-bearing application. The samples were prepared using the powder metallurgy process. The powders of both materials were homogeneously mixed in the quantified proportions to form the uniform mixture. For the fabrication of samples, the planning of experiments was done with the central composite design. The effect of process factors such as the weight percentage of hydroxyapatite, compaction pressure, and microwave sintering factors such as sintering temperature, heating rate, and soaking time on the compressive yield strength and sintered density was evaluated. Cylindrical samples were prepared for compression testing. The experimental results exhibited the increase in the compressive yield strength as well as the sintered density with the decrease in the hydroxyapatite percentage and an increase in the compaction pressure. The results also revealed that the compressive yield strength and sintered density were found to be increased as the heating rate and sintering temperature increased. Sample characterization was carried out for phase determination and composition of the elements. The optimum process factors were obtained after the regression analysis, and the results of the optimum process factors were also verified with the confirmation experiments. The in vitro corrosion testing of the sample prepared with optimum factors was also carried out in the simulated body fluid at a temperature of 37 ± 0.5 ℃. The fabricated sample showed a good agreement between the mechanical and degradation properties as required for a human bone.

show abstract

Corrosion behaviour of the porous iron scaffold in simulated body fluid for biodegradable implant application

Cited by 68 publications

References 51 publications

Degradation Performance of Open-Cell Biomaterials from Phosphated Carbonyl Iron Powder with PEG Coating

Degradation Performance of Open-Cell Biomaterials from Phosphated Carbonyl Iron Powder with PEG Coating

Evaluation of in vitro corrosion behavior of zinc–hydroxyapatite and zinc–hydroxyapatite–iron as biodegradable composites

An experimental investigation of the fabrication of biodegradable zinc–hydroxyapatite composite material using microwave sintering

Contact Info

Product

Resources

About