Corticosteroid Treatment and Surgery. 2. The Management of Steroid Cover

Plumpton, F. S.; Besser, G. M.; Cole, P. V.

doi:10.1097/00132586-197002000-00020

Cited by 10 publications

(14 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The drug groups are composed of steroidal and non-steroidal anti-inflammatory agents, and can later include several agents, such as antimalarials, sulfasalazine, penicillin, azathioprine, methotrexate, and cyclosporine A. The anesthesiologist should be attentive to the adverse effects of these drugs, which can influence anesthetic technique 17 .…”

Section: Therapymentioning

confidence: 99%

Anestesia e artrite reumatoide

Vieira¹,

Goodman²,

Tanaka³

2011

Rev. Bras. Anestesiol.

View full text Add to dashboard Cite

Summary: Vieira EM, Goodman S, Tanaka PP -Anesthesia and Rheumatoid Arthritis. Background and objectives:Rheumatoid arthritis (RA) is a chronic inflammatory disease of unknown etiology. It is known that RA patients have a reduced life expectancy when compared with the general population. Rheumatic diseases are numerous and occur with high variability; some of them develop very rapidly while others occur chronically provoking disability throughout life. Anesthetic risks in osteoarticular disorders involve not only the mechanical deformations caused by the disease, but also the cardiovascular, respiratory, renal, and digestive systems.

show abstract

Section: Therapymentioning

confidence: 99%

Anestesia e artrite reumatoide

Vieira¹,

Goodman²,

Tanaka³

2011

Rev. Bras. Anestesiol.

View full text Add to dashboard Cite

show abstract

“…This is followed by 100 mg intramuscularly every 6 hours for 48e72 hours. Intravenous hydrocortisone produces inadequately sustained steroid levels 11 and so 25 mg at induction should be followed by an infusion at 5 mg/hour. 12 Risks of glaucoma, cataracts, hypersensitivity reactions and candidiasis have been reported, but are infrequent.…”

Section: Immunomodulatorsmentioning

confidence: 99%

Respiratory system: applied pharmacology

Saul¹,

Kendall²

2011

Anaesthesia & Intensive Care Medicine

View full text Add to dashboard Cite

Manipulation of respiratory physiology by pharmacological intervention is a significant role of the anaesthetist and intensivist. Successful use of these various agents requires a thorough understanding of their mechanisms of actions, potential side effects and limitations. These interventions involve changes in airway calibre, secretions and sensitivity of the airway to noxious stimuli. Other agents act to inhibit the depressant effect that sedatives may have on the patient's respiratory drive. The effects, both advantageous and detrimental, may be complicated by the action of other disease processes which affect the metabolism of these drugs. There are multiple possible routes of administration which allows flexibility for the clinician and may reduce systemic effects, thereby limiting side effect profiles. Drugs used specifically in the treatment of acute respiratory distress syndrome attempt to alter pulmonary ventilation and perfusion thereby reduce mismatching and improve diffusion capacity.

show abstract

“…Differences in the methods of assessment of the HPA axis probably account for the huge variability in reported recovery times. Plumpton and Besser suggested 2 months as the maximum interval following treatment during which recovery of the HPA may be incomplete [6], while La Rochelle and colleagues found that the duration of therapy, total steroid dose and highest steroid dose administered did not affect HPA recovery [38]. Based on this evidence, we suggest that patients who have taken steroids in excess of 10 mg prednisolone, or equivalent, within 3 months of surgery, should be considered to have some degree of HPA suppression and receive a low-dose replacement regimen according to the magnitude of surgery.…”

Section: Steroid Treatment Regimensmentioning

confidence: 99%

“…Of the 20 patients currently receiving long-term steroid therapy, 10 patients were receiving replacement therapy for Addison's disease, hypopituitarism or following adrenalectomy and the remaining 10 patients were receiving immunosuppressive therapy for unspecified conditions [6]. The patients treated previously had received prednisolone, or equivalent, in doses ranging from 5 to 50 mg.day ¹1 for between 6 days and 10 years; the interval since treatment varied from 3 days to 24 months.…”

mentioning

confidence: 99%