Cortisone and A.C.T.H. in Treatment of Non-rheumatic Conditions

Spontaneous and Induced Water Intoxication in Two Cases of Hypopituitarism

“…It is not surprising, therefore, that pure water retention without significant sodium depletion can occur in hypopituitarism. That it may not be uncommon is suggested by reports of very low plasma sodium concentrations, without evidence of dehydration or crisis, in patients with this conditionfor example Bartter et al (1950), Waterhouse et al (1952, Peters et al (1954), andAber et al (1954)-a state of affairs which has usually been attributed to sodium depletion.…”

Results of Partial Gastrectomy in Treatment of Peptic Ulcer

“…That it may not be uncommon is suggested by reports of very low plasma sodium concentrations, without evidence of dehydration or crisis, in patients with this conditionfor example Bartter et al (1950), Waterhouse et al (1952), Peters et al (1954), and Aber et al (1954)-a state of affairs which has usually been attributed to sodium depletion.…”

Diagnosis and Treatment of Hypopituitarism

“…Table III shows the results obtained with a combination of all these tests. It will be seen that two out of three tests have proved abnormal in 37 out of 40 cases of hypopituitarism reported during the past few years, and their Sheehan, 1951;Robertson and Kirkpatrick, 1951;Rolland and Matthews, 1952;Hart, 1953;Aber et al, 1954). We first started treating some of our patients with A.C.T.H.…”

“…once or twice weekly, there seems to be no reason why satisfactory treatment cannot be continued indefinitely. Aber et al (1954) report three patients who are being maintained in good health with weekly injections of 40 units of " acthar gel. "…”