Cosmetic and radiological outcome following the use of synthetic hydroxyapatite porous-dense bilayer burr-hole buttons

Easwer, H. V.; Rajeev, A.; Varma, H. K.; Vijayan, Sekhara Pillai; Bhattacharya, R. N.

doi:10.1007/s00701-007-1131-3

Cited by 29 publications

(18 citation statements)

References 10 publications

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“…For example, bulk materials, available in dense and porous forms, are used for alveolar ridge augmentation, immediate tooth replacement and maxillofacial reconstruction [4]. Other examples comprise burr-hole buttons [597,598], orbital implants (including Bio-Eye ® ) [599,600,601,602,603,604,605,606], increment of the hearing ossicles [607,608,609], spine fusion [610,611,612,613] and repair of bone defects [138,614,615]. In order to permit growth of new bone into defects, a suitable bioresorbable material should fill these defects.…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Calcium Orthophosphate-Based Bioceramics

Dorozhkin¹

2013

Materials

232

153

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Various types of grafts have been traditionally used to restore damaged bones. In the late 1960s, a strong interest was raised in studying ceramics as potential bone grafts due to their biomechanical properties. A bit later, such synthetic biomaterials were called bioceramics. In principle, bioceramics can be prepared from diverse materials but this review is limited to calcium orthophosphate-based formulations only, which possess the specific advantages due to the chemical similarity to mammalian bones and teeth. During the past 40 years, there have been a number of important achievements in this field. Namely, after the initial development of bioceramics that was just tolerated in the physiological environment, an emphasis was shifted towards the formulations able to form direct chemical bonds with the adjacent bones. Afterwards, by the structural and compositional controls, it became possible to choose whether the calcium orthophosphate-based implants remain biologically stable once incorporated into the skeletal structure or whether they were resorbed over time. At the turn of the millennium, a new concept of regenerative bioceramics was developed and such formulations became an integrated part of the tissue engineering approach. Now calcium orthophosphate scaffolds are designed to induce bone formation and vascularization. These scaffolds are often porous and harbor different biomolecules and/or cells. Therefore, current biomedical applications of calcium orthophosphate bioceramics include bone augmentations, artificial bone grafts, maxillofacial reconstruction, spinal fusion, periodontal disease repairs and bone fillers after tumor surgery. Perspective future applications comprise drug delivery and tissue engineering purposes because calcium orthophosphates appear to be promising carriers of growth factors, bioactive peptides and various types of cells.

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Section: Biomedical Applicationsmentioning

confidence: 99%

Calcium Orthophosphate-Based Bioceramics

Dorozhkin¹

2013

Materials

232

153

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“…Although these bone defects were usually directly covered by scalp without repair, they may lead to further risks, such as leakage of cerebrospinal fluid or infection [84]. Moreover, the scalp depression at the defect sites also influence cosmetic outcomes after the surgery [85]. …”

Section: Clinical Applications Of Mineralized Collagen Productsmentioning

confidence: 99%

“…Autologous bone and many artificial bone grafts were used to repair or fill the defects on the skull [84,85,86]. However, harvesting autologous bone from the inner side of the skull flap reduces its thickness, and the amount of such an autograft is limited.…”

Section: Clinical Applications Of Mineralized Collagen Productsmentioning

confidence: 99%

Mineralized Collagen: Rationale, Current Status, and Clinical Applications

et al. 2015

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This paper presents a review of the rationale for the in vitro mineralization process, preparation methods, and clinical applications of mineralized collagen. The rationale for natural mineralized collagen and the related mineralization process has been investigated for decades. Based on the understanding of natural mineralized collagen and its formation process, many attempts have been made to prepare biomimetic materials that resemble natural mineralized collagen in both composition and structure. To date, a number of bone substitute materials have been developed based on the principles of mineralized collagen, and some of them have been commercialized and approved by regulatory agencies. The clinical outcomes of mineralized collagen are of significance to advance the evaluation and improvement of related medical device products. Some representative clinical cases have been reported, and there are more clinical applications and long-term follow-ups that currently being performed by many research groups.

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“…The dura mater is closed and bone fl ap replaced. Hydroxyapatite burr hole buttons [13] were used to cover the burr hole defect on the cranium in all but three patients. All patients were subjected to CT scanning of the brain on the fi rst postoperative day.…”

Section: Operative Techniquementioning

confidence: 99%