Tan, for offering their help and suggestions on the study design, and my roomie, Dr. Wan Wei, for the small talks that have lightened my days when writing this thesis. I am very grateful to my parents, Mr. Zhaode Zeng and Ms. Zhengrong Lai, who have always supported me to pursue what I want.Lastly, to my companion, my soulmate, and my husband, Wangran, for his unconditional love and support, for his unparalleled patience, for believing in me more than I do, and for always encouraging me to become a better self. vi