2021
DOI: 10.21292/2075-1230-2021-99-2-6-15
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COVID-19 and chronic obstructive pulmonary disease: what is known about the unknown

Abstract: The article reviews 60 publications and addresses key aspects of concurrent COVID-19 and chronic obstructive pulmonary disease (COPD). It presents data stating that COPD patients have higher expression of the receptor of angiotensin-converting enzyme 2 in the lungs and this may contribute to a greater susceptibility to COVID-19. In COPD, signs of endothelial cell dysfunction and tendency to thrombus formation have been identified which can present the risk of unfavorable outcomes of COVID-19. Cohort study data… Show more

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Cited by 6 publications
(1 citation statement)
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“…Moreover, in COPD, supraventricular arrhythmias are observed in 77%, AF was observed in 8% of patients, and the risk of AF hospitalization was higher among patients with a low FEV1 60% [ 35 ]. Some researchers [ 36 ] presented a review of 60 literature sources regarding the comorbidity of COVID-19 and COPD. It is evident that COPD patients have increased the expression of the angiotensin-converting enzyme 2 receptor in the lungs, which may contribute to a greater susceptibility to COVID-19.…”
Section: Resultsmentioning
confidence: 99%
“…Moreover, in COPD, supraventricular arrhythmias are observed in 77%, AF was observed in 8% of patients, and the risk of AF hospitalization was higher among patients with a low FEV1 60% [ 35 ]. Some researchers [ 36 ] presented a review of 60 literature sources regarding the comorbidity of COVID-19 and COPD. It is evident that COPD patients have increased the expression of the angiotensin-converting enzyme 2 receptor in the lungs, which may contribute to a greater susceptibility to COVID-19.…”
Section: Resultsmentioning
confidence: 99%