COVID-19 and obesity: the meeting of two pandemics

Brandão, Simone Cristina Soares; Godoi, Emmanuelle Tenório Albuquerque Madruga; Cordeiro, Lúcia Helena de Oliveira; Bezerra, Camila; Ramos, Júlia de Oliveira Xavier; Arruda, Gustavo Freitas Alves de; Lins, Esdras Marques

doi:10.20945/2359-3997000000318

Cited by 13 publications

(11 citation statements)

References 83 publications

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“…According to the World Health Organization (WHO), between 1975 and 2016, the number of people with obesity in the world almost tripled, which means approximately 13% of the world’s adult population (11% of men and 15% of women) were people with obesity in 2016. This fact leads the WHO to consider obesity as the global epidemic of the 21st century [ 1 ], even above the current COVID-19 pandemic [ 2 ]. Particularly, people with overweight and obesity are closely associated with the development of hypertension, cardiovascular disease, diabetes, dyslipidemia, and some types of cancer, among other diseases and comorbidities [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

From Young to Older, the 4 Phases Method Is Efficient in Promoting Quick Weight, BMI, and Waist Circumference Reductions

Ramuth

Roseira³

et al. 2022

Healthcare

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Background: Investigate the effectiveness of the scientific 4 Phases Method, a methodology developed by EMAGRECENTRO, which is based on a ketogenic approach (total carbohydrate intake <40 g/day; including fibers) associated with health coach assistance, in promoting reductions in body weight, body mass index (BMI), and waist circumference after 5 weeks of methodology application. Methods: Record files from 354 individuals, both sexes, aged between 18 and 67, who took part in the 4 Phases Method were used to develop this study. Age, sex, weight, height, BMI, waist circumference measurement, and the presence of ketone bodies in the urine were evaluated before (baseline) and after 5 weeks of the 4 Phases application. Results: In general, a significant reduction in body weight (−7.8 ± 1.2 kg, p < 0.0001), BMI (−2.8 ± 0.4 kg/m2, p < 0.0001), and waist circumference measurement (−7.6 ± 0.4 cm, p < 0.0001) was found after the application of the 4 Phases Method, regardless of age, gender, and BMI. Conclusions: Taken together, our results demonstrated that the 4 Phases Method was able to promote significant body weight, BMI, and waist circumference reductions in the short term, particularly by associating a ketogenic intake strategy with a regular close follow-up weekly consultation with a health coach assistance.

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Section: Introductionmentioning

confidence: 99%

From Young to Older, the 4 Phases Method Is Efficient in Promoting Quick Weight, BMI, and Waist Circumference Reductions

Ramuth

Roseira³

et al. 2022

Healthcare

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“…This change in profile may result from improved reporting, with a consequent decrease in missing data. Perhaps scientific evidence indicating the importance of these comorbidities in influencing the severe form of COVID-19 ( 42 - 43 ) encouraged improved reporting.…”

Section: Discussionmentioning

confidence: 99%

Factors associated with death among postpartum women with COVID-19: a Brazilian population-based study

Bonatti

Miller

Carvalhães

et al. 2021

Rev. Latino-Am. Enfermagem

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Objective: to identify the factors associated with death due to COVID-19 among Brazilian postpartum women in the first five months of the pandemic and five subsequent months, and describe the sociodemographic and clinical characteristics of postpartum women who developed the disease. Method: cross-sectional population-based study using a secondary database available in the Sistema de Informação de Vigilância Epidemiológica da Gripe -SIVEP-Gripe (Influenza Epidemiological Surveillance Information System), Brazilian Ministry of Health. A total of 869 postpartum women were included, and the analysis considered the first five months of the pandemic and subsequent five months. Association between the variables of interest and outcome (death due to COVID-19/cure) was investigated using logistic regression. Results: most participants were aged between 20 and 34, of mixed race or Caucasian, and lived in the urban/peri-urban area. The proportion of deaths was 20.2% in the first period and 11.2% in the second. The likelihood of death increased in both periods due to the presence of respiratory signs and symptoms: dyspnea, respiratory distress, and oxygen saturation below 95%, in addition to the need for ventilatory support and intensive care. Conclusion: the proportion of deaths among postpartum women was high and decreased in the second period under study. Respiratory signs and symptoms, mechanical ventilation, and intensive care were associated with death in both periods.

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“…38 Immune dysregulation, which tends to occur in obese individuals affected by COVID-19, may be related to a phenomenon known as hypercytokinemia or "cytokine storm. " 39 However, Brandão et al 40 have indicated that the initial immune response is very weak considering the high SARS-CoV-2 viral load, which justifies the excessive recruitment of cytokines. This mechanism of action is aggravated by viral overload in epithelial cells, especially in the lungs, causing the collapse of these structures.…”

Section: Obesity and Covid-19mentioning

confidence: 99%

Molecular aspects of COVID-19 and its relationship with obesity and physical activity: a narrative review

et al. 2023

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BACKGROUND: Severe acute respiratory syndrome coronavirus 2 has several mechanisms of action related to inflammatory responses, especially in individuals diagnosed with obesity. This hyperinflammatory clinical profile resulting from the association between obesity and coronavirus disease 2019 (COVID-19) may be attenuated by regular physical activity. OBJECTIVE: The aim of this study was to review the evidence on the consequences of physical inactivity and physical activity on COVID-19 in patients with obesity. DESIGN AND SETTING: Narrative review at the Bahiana School of Medicine and Public Health in Salvador, Brazil. METHODS: We searched evidence on the association of COVID-19 with physical activity and obesity using the following keywords: "covid-19, " "physical activity, " and "obesity". The databases used were MEDLINE (PubMed), ScienceDirect, and Virtual Health Library. Studies published from 2019 to 2021 and available in Portuguese, English, and Spanish were included. The final search was conducted on September 26, 2021. RESULTS: We identified 661 studies in the database, among which 71 were considered for inclusion in the narrative review of the molecular aspects of COVID-19 and its relationship with physical activity and obesity. CONCLUSION: This literature review enabled the perception of the relationship between the molecular mechanisms of COVID-19 and obesity. Regular physical activity had various benefits for the inflammatory condition of the studied population, highlighting moderate-intensity..

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COVID-19 and obesity: the meeting of two pandemics

Cited by 13 publications

References 83 publications

From Young to Older, the 4 Phases Method Is Efficient in Promoting Quick Weight, BMI, and Waist Circumference Reductions

From Young to Older, the 4 Phases Method Is Efficient in Promoting Quick Weight, BMI, and Waist Circumference Reductions

Factors associated with death among postpartum women with COVID-19: a Brazilian population-based study

Molecular aspects of COVID-19 and its relationship with obesity and physical activity: a narrative review

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