A better understanding of automation disengagements can lead to improved safety and efficiency of automated systems. This study investigates the factors contributing to automation disengagements initiated by human operators and the automation itself by analyzing semi-structured interviews with 103 users of Tesla’s Autopilot and FSD Beta. The factors leading to automation disengagements are represented by categories. In total, we identified five main categories, and thirty-five subcategories. The main categories include human operator states (5), human operator’s perception of the automation (17), human operator’s perception of other humans (3), the automation’s perception of the human operator (3), and the automation incapability in the environment (7). Human operators disengaged the automation when they anticipated failure, observed unnatural or unwanted automation behavior (e.g., erratic steering, running red lights), or believed the automation is not capable to operate safely in certain environments (e.g., inclement weather, non-standard roads). Negative experiences of human operators, such as frustration, unsafe feelings, and distrust represent some of the adverse human operate states leading to automation disengagements initiated by human operators. The automation, in turn, monitored human operators and disengaged itself if it detected insufficient vigilance or speed rule violations by human operators. Moreover, human operators can be influenced by the reactions of passengers and other road users, leading them to disengage the automation if they sensed discomfort, anger, or embarrassment due to the automation’s actions. The results of the analysis are synthesized into a conceptual framework for automation disengagements, borrowing ideas from the human factor's literature and control theory. This research offers insights into the factors contributing to automation disengagements, and highlights not only the concerns of human operators but also the social aspects of this phenomenon. The findings provide information on potential edge cases of automated vehicle technology, which may help to enhance the safety and efficiency of such systems.