“…Most of the insights concerning the CBRIS model are therefore derived from qualitative case studies. These studies include investigations into company-level cross-border innovation cooperation (van den Broek et al, 2018aBroek et al, , 2018b, the role of universities and non-profit organizations in cross-border integration (van den Broek et al, 2019;Cappellano and Makkonen, 2020b;Cappellano et al, 2020), the impact of institutional change and funding programmes on crossborder innovation cooperation (Peck and Mulvey, 2018;Makkonen et al, 2018b;Miörner et al, 2018) and the potential for adopting common cross-border innovation policies (Tõnurist and Kattel, 2017;Muller et al, 2017). These studies have shown that even CBRs with relatively high levels of (cognitive, cultural, institutional, social or geographical) proximity report low levels of cross-border innovation connections and integration, in contrast to what is suggested in the conceptual definition of a strongly integrated CBRIS by Lundquist and Trippl (2013).…”