Cross-sectional growth of children whose mothers abused amphetamines during pregnancy

Eriksson, Margareta; Jonsson, Björn; Steneroth, Gun; Zetterström, Rolf

doi:10.1111/j.1651-2227.1994.tb13091.x

Cited by 35 publications

(26 citation statements)

References 21 publications

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“…The most extensive followup data on affective, behavioral, and cognitive outcomes following prenatal AMPHs are provided by Swedish researchers who tracked a cohort of 65 AMPH-exposed children from birth to age 14. They reported in children with continuous AMPH exposure throughout gestation, a variety of adverse physical, cognitive, emotional, and social effects, including increased prevalence of ADHD, aggression, and learning difficulties attributed to deficits in attention, memory, and motivation (Eriksson et al, 1994;Eriksson et al, 2000). Furthermore, a relationship between head circumference at birth and at 1 year of age predicted language and mathematics proficiency at 14 years of age (Eriksson et al, 2000).…”

Section: Amphetaminementioning

confidence: 99%

Developmental Consequences of Fetal Exposure to Drugs: What We Know and What We Still Must Learn

Ross

Graham

Money

et al. 2014

Neuropsychopharmacol

342

241

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Most drugs of abuse easily cross the placenta and can affect fetal brain development. In utero exposures to drugs thus can have long-lasting implications for brain structure and function. These effects on the developing nervous system, before homeostatic regulatory mechanisms are properly calibrated, often differ from their effects on mature systems. In this review, we describe current knowledge on how alcohol, nicotine, cocaine, amphetamine, Ecstasy, and opiates (among other drugs) produce alterations in neurodevelopmental trajectory. We focus both on animal models and available clinical and imaging data from cross-sectional and longitudinal human studies. Early studies of fetal exposures focused on classic teratological methods that are insufficient for revealing more subtle effects that are nevertheless very behaviorally relevant. Modern mechanistic approaches have informed us greatly as to how to potentially ameliorate the induced deficits in brain formation and function, but conclude that better delineation of sensitive periods, dose-response relationships, and long-term longitudinal studies assessing future risk of offspring to exhibit learning disabilities, mental health disorders, and limited neural adaptations are crucial to limit the societal impact of these exposures.

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Section: Amphetaminementioning

confidence: 99%

Developmental Consequences of Fetal Exposure to Drugs: What We Know and What We Still Must Learn

Ross

Graham

Money

et al. 2014

Neuropsychopharmacol

342

241

View full text Add to dashboard Cite

show abstract

“…However, 1 study of unspecified amphetamine use suggests that in utero exposure may be associated with poor growth throughout early childhood. 192 …”

Section: Long-term Effects Related To Prenatal Drug Exposure Growthmentioning

confidence: 99%

Prenatal Substance Abuse: Short- and Long-term Effects on the Exposed Fetus

Behnke¹,

Levy²,

Ammerman³

et al. 2013

Pediatrics

497

389

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Prenatal substance abuse continues to be a significant problem in this country and poses important health risks for the developing fetus. The primary care pediatrician’s role in addressing prenatal substance exposure includes prevention, identification of exposure, recognition of medical issues for the exposed newborn infant, protection of the infant, and follow-up of the exposed infant. This report will provide information for the most common drugs involved in prenatal exposure: nicotine, alcohol, marijuana, opiates, cocaine, and methamphetamine.

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“…In a study of 65 children born to mothers in Sweden who had abused amphetamines during their pregnancy, the mean birth weight, height, and head circumference were below the means of their unexposed peers. 15 …”

mentioning

confidence: 99%

The Effects of Prenatal Methamphetamine Exposure on Childhood Growth Patterns from Birth to 3 Years of Age

et al. 2011

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We examined the effects of prenatal methamphetamine (MA) exposure on growth parameters from birth to age 3 years. The 412 subjects included (n = 204 exposed) were enrolled at birth in the Infant Development, Environment and Lifestyle study, a longitudinal study assessing the effects of prenatal MA exposure on childhood outcomes. Individual models were used to examine the effects of prenatal MA exposure on weight, head circumference, height, and weight-for-length growth trajectories. After adjusting for covariates, height trajectory was lower in the exposed versus the comparison children (p = 0.021) over the first 3 years of life. Both groups increased height on average by 2.27 cm per month by age 3 years. In term subjects, MA exposure was also associated with a lower height trajectory (p = 0.034), with both the exposed and comparison groups gaining 2.25 cm per month by age 3 years. There was no difference in weight, head circumference, or weight-for-length growth trajectories between the comparison and the exposed groups. Children exposed prenatally to MA have a modest decrease in height growth trajectory during the first 3 years of life with no observed difference in weight, head circumference, or weight-for-length trajectories.

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Cross-sectional growth of children whose mothers abused amphetamines during pregnancy

Cited by 35 publications

References 21 publications

Developmental Consequences of Fetal Exposure to Drugs: What We Know and What We Still Must Learn

Developmental Consequences of Fetal Exposure to Drugs: What We Know and What We Still Must Learn

Prenatal Substance Abuse: Short- and Long-term Effects on the Exposed Fetus

The Effects of Prenatal Methamphetamine Exposure on Childhood Growth Patterns from Birth to 3 Years of Age

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