Cross-species extrapolation of chronic nickel Biotic Ligand Models

Schlekat, Christian E.; Genderen, Eric Van; Schamphelaere, Karel A.C. De; Antunes, Paula M.C.; Rogevich, Emily C.; Stubblefield, William A.

doi:10.1016/j.scitotenv.2010.09.012

Cited by 99 publications

(161 citation statements)

References 23 publications

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“…In comparison, a similar study by Schlekat et al [3] in APHA media, with 1 mg/L of Suwannee River NOM instead, resulted in IC50 NiTot 136.8 mg/L; the inclusion of higher DOC in this study would have reduced the bioavailability of Ni and would partially explain the higher toxicity threshold. Wang [25] observed a mean Ni toxicity (IC50) to L. minor of 330 mg/L using a shorter exposure of 96 h and an earlier version of the APHA medium that had a hardness of only 30 mg/L and a pH of 7.5, a much lower hardness and somewhat lower pH than the APHA medium used in the present study [26].…”

Section: Resultscontrasting

confidence: 46%

“…The BLM has been successfully implemented for fish and invertebrates for several metals. In contrast, Ni is the only metal for which the BLM has incorporated an aquatic plant for the purposes of Ni risk assessment [3]. It is plausible that plants may not follow competitive inhibition of trace metal uptake by major cations, as is the case for some aquatic organisms [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

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Effect of major cations (Ca²⁺, Mg²⁺, Na⁺, K⁺) and anions (SO, Cl⁻, NO) on Ni accumulation and toxicity in aquatic plant (Lemna minor L.): Implications For Ni risk assessment

Gopalapillai

Hale

Vigneault

2013

Enviro Toxic and Chemistry

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Abstract-The effect of major cation activity (Ca 2þ , Mg 2þ , Na þ , K þ ) on Ni toxicity, with dose expressed as exposure (total dissolved Ni concentration Ni Tot ) or free Ni ion activity (in solution Ni 2þ ), or as tissue residue (Ni concentration in plant tissue Ni Tiss ) to the aquatic plant Lemna minor L. was examined. In addition, Ni accumulation kinetics was explored to provide mechanistic insight into current approaches of toxicity modeling, such as the tissue residue approach and the biotic ligand model (BLM), and the implications for plant Ni risk assessment. Major cations did not inhibit Ni accumulation via competitive inhibition as expected by the BLM framework. For example, Ca 2þ and Mg 2þ (sulfate as counter-anion) had an anticompetitive effect on Ni accumulation, suggesting that Ca or Mg forms a ternary complex with Ni-biotic ligand. The counter-anion of the added Ca (sulfate, chloride, or nitrate) affected plant response (percentage of root growth inhibition) to Ni. Generally, sulfate and chloride influenced plant response while nitrate did not, even when compared within the same range of Ca 2þ , which suggests that the anion dominated the observed plant response. Overall, although an effect of major cations on Ni toxicity to L. minor L. was observed at a physiological level, Ni 2þ or Ni Tot alone modeled plant response, generally within a span of twofold, over a wide range of water chemistry. Thus, consideration of major cation competition for improving Ni toxicity predictions in risk assessment for aquatic plants may not be necessary. Environ. Toxicol. Chem. 2013;32:810-821. # 2013 SETAC

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Section: Resultscontrasting

confidence: 46%

Section: Introductionmentioning

confidence: 99%

Effect of major cations (Ca²⁺, Mg²⁺, Na⁺, K⁺) and anions (SO, Cl⁻, NO) on Ni accumulation and toxicity in aquatic plant (Lemna minor L.): Implications For Ni risk assessment

Gopalapillai

Hale

Vigneault

2013

Enviro Toxic and Chemistry

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“…The influence of water chemistry on Ni bioavailability and chronic ecotoxicology is now well established with the development and validation of biotic ligand models (BLMs) [18], which were used in a generic assessment of risks to the environment from the use of Ni. Through the use of these models it is possible to normalize all of the chronic ecotoxicity data in the data set to specific water chemistry conditions and then plot a species sensitivity distribution to derive a site-specific 5% hazardous concentration of species or the 95% protection level.…”

Section: Historical Background To the Use Of Bioavailability In Regulmentioning

confidence: 99%

Accounting for metal bioavailability in assessing water quality: A step change?

Merrington¹,

Peters²,

Schlekat

2016

Enviro Toxic and Chemistry

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Abstract-Bioavailability of metals to aquatic organisms can be considered to be a combination of the physicochemical factors governing metal behavior and the specific pathophysiological characteristics of the organism's biological receptor. Effectively this means that a measure of bioavailability will reflect the exposures that organisms in the water column actually "experience". This is important because it has long been established that measures of total metal in waters have limited relevance to potential environmental risk. The concept of accounting for bioavailability in regard to deriving and implementing environmental water quality standards is not new, but the regulatory reality has lagged behind the development of scientific evidence supporting the concept. Practical and technical reasons help to explain this situation. For example, concerns remain from regulators and the regulated that the efforts required to change existing systems of metal environmental protection that have been in place for over 35 yr are so great as not to be commensurate with likely benefits. However, more regulatory jurisdictions are now considering accounting for metal bioavailability in assessments of water quality as a means to support evidence-based decision-making. In the past decade, both the US Environmental Protection Agency and the European Commission have established bioavailability-based standards for metals, including Cu and Ni. These actions have shifted the debate toward identifying harmonized approaches for determining when knowledge is adequate to establish bioavailability-based approaches and how to implement them. Environ Toxicol Chem 2016;35:257-265. # 2016 SETAC

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“…The acute data available for one gastropod species, Babylonia areolata indicates that juveniles are sensitive to nickel (acute survival, 96 h, inhibited by 50% (EC50 at 200 µg Ni L -1 ) (Hajimad and Vedamanikam 2013;Vedamanikam and Hajimad 2013; Table 4). The widely distributed snail Lymnaea stagnalis has been shown to be among the most sensitive species to nickel exposure (Nys et al 2016, Niyogi et al 2014, Schlekat et al 2010, with chronic juvenile growth inhibited by concentrations as low as 1.3 µg Ni L -1 , following 30 days of exposure (Niyogi et al 2014). …”

Section: Marinementioning

confidence: 99%

A review of nickel toxicity to marine and estuarine tropical biota with particular reference to the South East Asian and Melanesian region

Gissi

Stauber

Binet

et al. 2016

Environmental Pollution

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. (2016). A review of nickel toxicity to marine and estuarine tropical biota with particular reference to the South East Asian and Melanesian region. Environmental Pollution, 218 1308Pollution, 218 -1323 A review of nickel toxicity to marine and estuarine tropical biota with particular reference to the South East Asian and Melanesian region AbstractThe South East Asian Melanesian (SEAM) region contains the world's largest deposits of nickel lateritic ores. Environmental impacts may occur if mining operations are not adequately managed. Effects data for tropical ecosystems are required to assess risks of contaminant exposure and to derive water quality guidelines (WQG) to manage these risks. Currently, risk assessment tools and WQGs for the tropics are limited due to the sparse research on how contaminants impact tropical biota. As part of a larger project to develop appropriate risk assessment tools to ensure sustainable nickel production in SEAM, nickel effects data were required. The aim of this review was to compile data on the effects of nickel on tropical marine, estuarine, pelagic and benthic species, with a particular focus on SEAM. There were limited high quality chronic nickel toxicity data for tropical marine species, and even fewer for those relevant to SEAM. Of the data available, the most sensitive SEAM species to nickel were a sea urchin, copepod and anemone. There is a significant lack of high quality chronic data for several ecologically important taxonomic groups including cnidarians, molluscs, crustaceans, echinoderms, macroalgae and fish. No high quality chronic nickel toxicity data were available for estuarine waters or marine and estuarine sediments. The very sparse toxicity data for tropical species limits our ability to conduct robust ecological risk assessment and may require additional data generation or readacross from similar species in other databases (e.g. temperate) to fill data gaps. Recommendations on testing priorities to fill these data gaps are presented. Capsule abstractNickel toxicity data is lacking for tropical marine biota; data is required for key taxa including cnidarians, molluscs, crustaceans, echinoderms, macroalgae and fish. HighlightsSouth East Asia and Melanesia contains the largest deposits of nickel lateritic ores Environmental impacts may occur if mining operations are not adequately managed Risk assessment tools for nickel in the tropics are limited due to lack of data We compiled nickel data for aquatic tropical ecosystems and identified key gaps Nickel data is required for corals, molluscs, crustaceans, echinoderms, macroalgae, fish KeywordsMining, tropical ecotoxicology, ecological risk assessment, bioassay, species sensitivity distribution. 2 AbstractThe South East Asian Melanesian (SEAM) region contains the world's largest deposits of nickel lateritic ores. Environmental impacts may occur if mining operations are not adequately managed. Effects data for tropical ecosystems are required to assess risks of contaminant exposure and to derive water quality ...

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Cross-species extrapolation of chronic nickel Biotic Ligand Models

Cited by 99 publications

References 23 publications

Effect of major cations (Ca²⁺, Mg²⁺, Na⁺, K⁺) and anions (SO, Cl⁻, NO) on Ni accumulation and toxicity in aquatic plant (Lemna minor L.): Implications For Ni risk assessment

Effect of major cations (Ca²⁺, Mg²⁺, Na⁺, K⁺) and anions (SO, Cl⁻, NO) on Ni accumulation and toxicity in aquatic plant (Lemna minor L.): Implications For Ni risk assessment

Accounting for metal bioavailability in assessing water quality: A step change?

A review of nickel toxicity to marine and estuarine tropical biota with particular reference to the South East Asian and Melanesian region

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Cross-species extrapolation of chronic nickel Biotic Ligand Models

Cited by 99 publications

References 23 publications

Effect of major cations (Ca2+, Mg2+, Na+, K+) and anions (SO, Cl−, NO) on Ni accumulation and toxicity in aquatic plant (Lemna minor L.): Implications For Ni risk assessment

Effect of major cations (Ca2+, Mg2+, Na+, K+) and anions (SO, Cl−, NO) on Ni accumulation and toxicity in aquatic plant (Lemna minor L.): Implications For Ni risk assessment

Accounting for metal bioavailability in assessing water quality: A step change?

A review of nickel toxicity to marine and estuarine tropical biota with particular reference to the South East Asian and Melanesian region

Contact Info

Product

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Effect of major cations (Ca²⁺, Mg²⁺, Na⁺, K⁺) and anions (SO, Cl⁻, NO) on Ni accumulation and toxicity in aquatic plant (Lemna minor L.): Implications For Ni risk assessment

Effect of major cations (Ca²⁺, Mg²⁺, Na⁺, K⁺) and anions (SO, Cl⁻, NO) on Ni accumulation and toxicity in aquatic plant (Lemna minor L.): Implications For Ni risk assessment