CT-Guided Placement of Iodine-125 Seeds for Unresectable Carcinoma of the Lung

CT-guided interstitial brachytherapy of inoperable non-small cell lung cancer

“…Currently, only CT facilitates the appropriate image guidance for the treatment of lung tumors [19][20][21]. Sider et al [22] reported a case of CT guidance implantation of 125 I seeds for an unresectable carcinoma of the lung and achieved a successful distribution of seeds without complications. We used 125 I seed as the most common isotope, and 125 I seed placement has become a routine treatment for malignant tumors at various sites.…”

CT-guided permanent brachytherapy for patients with medically inoperable early-stage non-small cell lung cancer (NSCLC)

“…While PIB has been used with some success in the intraoperative treatment of unresectable, residual, or medically inoperable NSCLC since the 1940s [12][13][14], its use in a percu- taneous CT-guided approach is merely anecdotal [9,15,16]. This fact may be explained in part by the lack of tradition even in the most experienced brachytherapy centers, the small number of suitable candidates that probably stands for less than 20% of those referred for radical radiation due to a poor surgical risk and the fear of acute complications associated with the procedure.…”

Radioactive Seed Implantation and Lobaplatin Chemotherapy Are Safe and Effective in Treating Patients with Advanced Lung Cancer

“…In recent years, with the patients' increasing requirement on the disease therapies and the development of micro-invasive techniques, radioactive seed implantation has achieved rapid progression in the treatment of malignant tumors. 125 I seeds can cure patients with lung cancer through killing tumor cells by continuously releasing X-ray with radioactive nucleus (Sider et al, 1998;Martinez-Monge et al, 2008) 125 I seed source is small in size and low in dosage, with half-life period, average photon energy and tissue penetration distance being 59.6 d, 28 KeV and 1.7 cm, respectively. It can also release continuously lowdosage X-and γ-ray and effectively improve the dosage distribution ratio between locally radioactive tissues and normal tissues.…”