Cumulative lifetime attributed risks for patients subjected to contrast enhanced chest CT examinations

Dalah, Entesar Zawam; Obaideen, Abdulmunhem; Anam, Sabaa; Khalid, Malaz; Nadishani, Thilini; Hashim, Suhairul; Ghoshal, Sib Krishna

doi:10.1016/j.radphyschem.2021.109710

Cited by 3 publications

(1 citation statement)

References 23 publications

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“…Calculating D w using all slices of CT examination requires a long time and the use of a specific software package. In this work, average D w was calculated for ten central slices, which keep a percentage difference under 1% with an average of total slices according to Dalah et al [36].…”

Section: W Ed and Nd Calculationsmentioning

confidence: 99%

Feasibility of size-specific organ-dose estimates based on water equivalent diameter for common head CT examinations: a Monte Carlo study

Tahiri¹,

Benameur²,

Mkimel³

et al. 2023

J. Radiol. Prot.

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Computed tomography dose index (CTDI) is an unreliable dose estimate outside of the standard CTDI phantom diameters (16 and 32 cm). Size-specific dose estimate (SSDE) for head computed tomography (CT) examination was studied in the American Association of Physicists in Medicine Report 293 to provide SSDE coefficient factors based on water equivalent diameter as size metrics. However, it is limited to one protocol and for a fully irradiated organ. This study aimed to evaluate the dependency of normalized organ dose (ND) on water equivalent diameter as a size metric in three common protocols: routine head, paranasal sinus, and temporal bone. CTDIw measurements were performed for outlined protocols in the Siemens Emotion 16-slice-configuration scanner. Geant4 Application for Tomographic Emission Monte Carlo simulation platform, coupled with ten GSF patient models, was used to estimate organ doses. CT scanner system was modeled. Helical CT scans were simulated using constructor scan parameters and calculated scan lengths of each patient model. Organ doses provided by simulations were normalized to CTDIvol. The water equivalent diameters (D w) of patient models were obtained via relationships between D w and both effective diameter for a sample of patients’ data.NDs received by fully, partially, and non-directly irradiated organs were then reported as a function of D w. For fully irradiated organs, brain (R 2 > 0.92), eyes (R 2 > 0.88), and eye lens (R 2 > 0.89) correlate well with D w. For the rest of the results, a poor correlation was observed. For partially irradiated organs, the exception was scalp (R 2 = 0.93) in temporal bone CT. For non-directly irradiated organs, the exception was thyroid (R 2 > 0.90) and lungs (R 2 > 0.91) in routine head CT. ND correlates well in routine head CT than other protocols. For the most part, no relationship seems to exist between R 2 and scan percentage coverage. The results have revealed additional factors that may influence the ND and D w relationship, which explains the need for more studies in the future to investigate the effect of scan conditions and organ anatomy variation.

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Section: W Ed and Nd Calculationsmentioning

confidence: 99%

Feasibility of size-specific organ-dose estimates based on water equivalent diameter for common head CT examinations: a Monte Carlo study

Tahiri¹,

Benameur²,

Mkimel³

et al. 2023

J. Radiol. Prot.

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A closer look at utilized radiation doses during chest CT for COVID-19 patients

Khallouqi,

Sekkat,

Halimi

et al. 2024

Radiation Physics and Chemistry

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Incidence and Mortality Life-Attributable Risks for Patients Subjected to Recurrent CT Examinations and Cumulative Effective Dose Exceeding 100 mSv

Z. Dalah,

B. Mohamed,

M. Al Bastaki

et al. 2024

Clinics and Practice

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Computed tomography (CT) multi-detector array has been heavily utilized over the past decade. While transforming an individual’s diagnosis, the risk of developing pathogenesis as a result remains a concern. The main aim of this institutional cumulative effective dose (CED) review is to highlight the number of adult individuals with a record of CED ≥ 100 mSv over a time span of 5 years. Further, we aim to roughly estimate both incidence and mortality life-attributable risks (LARs) for the shortlisted individuals. CT studies performed over one year, in one dedicated trauma and emergency facility, were retrospectively retrieved and analyzed. Individuals with historical radiological CED ≥ 100 mSv were short-listed. LARs were defined and established based on organ, age and gender. Out of the 4406 CT studies reviewed, 22 individuals were found with CED ≥ 100 mSv. CED varied amongst the short-listed individuals, with the highest CED registered being 223.0 mSv, for a 57-year-old male, cumulated over an average study interval of 46.3 days. The highest median mortality risk was for females, 214 per 100,000 registered for the age group 51–60 years. While certain clinical indications and diseases require close follow-up using radiological examinations, the benefit-to-risk ratio should be carefully considered, particularly when CT is requested.

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Cumulative lifetime attributed risks for patients subjected to contrast enhanced chest CT examinations

Cited by 3 publications

References 23 publications

Feasibility of size-specific organ-dose estimates based on water equivalent diameter for common head CT examinations: a Monte Carlo study

Feasibility of size-specific organ-dose estimates based on water equivalent diameter for common head CT examinations: a Monte Carlo study

A closer look at utilized radiation doses during chest CT for COVID-19 patients

Incidence and Mortality Life-Attributable Risks for Patients Subjected to Recurrent CT Examinations and Cumulative Effective Dose Exceeding 100 mSv

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