Current Considerations in Surgical Treatment for Adolescents and Young Women with Breast Cancer

Abstract

Adolescents and young women (AYA) with breast cancer represent a unique patient population, compared to the general population with breast cancer. We performed a literature review to evaluate the factors that influenced the surgical outcomes in this patient population. Fifty-two studies were identified, which evaluated breast surgery type, axillary surgery, contralateral prophylactic mastectomy (CPM), surgical timing, psychological factors, disparities, and imaging use. AYA patients had equivalent oncologic outcomes with breast conserving surgery (BCS) or mastectomy. CPM did not improve survival. There are limited data on axillary management in the AYA population, and while more data would be beneficial, this is currently extrapolated from the general breast cancer population. A shorter time to initiate treatment correlated to better outcomes, and disparities need to be overcome for optimal outcomes. AYA patients appreciated involvement in clinical decisions, and shared decision making should be considered whenever possible. Providers must keep these factors in mind when counseling AYA patients, regarding the surgical management of breast cancer.

Effect of ABC Theory Model on Negative Emotion of Young Patients with Breast Cancer During Treatment

“…[1][2][3] Breast cancer in young women is characterized by late stage, high histological grade, high invasiveness, lymphatic vessel emboli, and bone marrow metastasis, compared with Western countries, its mortality and morbidity are increasing year by year. [4][5][6] Young women with breast cancer face more psychological problems, such as anxiety about a higher risk of recurrence, stress about marriage, childbirth, and work, negative emotions such as anxiety and depression often occur in different degrees during treatment, which lead to the decline of quality of life, immune function, poor treatment compliance, and aggravate the adverse reactions of treatment, etc., therefore, it is of great significance to pay attention to the research of negative emotion psychological intervention in young patients with breast cancer. [7][8][9] In addition, the diagnosis and treatment of breast cancer expose patients to both physical and psychological trauma.…”