2017
DOI: 10.1186/s13014-017-0766-3
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Current controversies in radiotherapy for breast cancer

Abstract: Multimodal treatment approaches have substantially improved the outcome of breast cancer patients in the last decades. Radiotherapy is an integral component of multimodal treatment concepts used in curative and palliative intention in numerous clinical situations from precursor lesions such as ductal carcinoma in situ (DCIS) to advanced breast cancer. This review addresses current controversial topics in radiotherapy with special consideration of DCIS, accelerated partial breast irradiation (APBI) and regional… Show more

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Cited by 42 publications
(32 citation statements)
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“…To achieve better therapeutic effect, we next experimented with four fractionated doses of 2 Gy IR which more closely mirrored the clinical IR treatment used in breast cancer [36]. VPA or HPTA were administrated before, during, and after IR treatment (Figure.…”
Section: Hpta Exhibits Radiosensitizing Properties To Ir Treatment Inmentioning
confidence: 99%
“…To achieve better therapeutic effect, we next experimented with four fractionated doses of 2 Gy IR which more closely mirrored the clinical IR treatment used in breast cancer [36]. VPA or HPTA were administrated before, during, and after IR treatment (Figure.…”
Section: Hpta Exhibits Radiosensitizing Properties To Ir Treatment Inmentioning
confidence: 99%
“…Breast cancer is the most common malignancy among women and the second leading cause of cancer deaths in women in the United States. 1 Locoregional treatment of breast cancer with radiation therapy has evolved over the past several decades, 2 which has been a critical component of the multimodal management of invasive breast cancer. 3 However, development of radioresistance becomes one of the most critical obstacles in cancer radiotherapy.…”
Section: ■ Introductionmentioning
confidence: 99%
“…Considerable controversy remains with respect to the use of radiotherapy for breast cancer (6). Firstly, it can be difficult to predict the patient's sensitivity to radiotherapy.…”
Section: Introductionmentioning
confidence: 99%