Cutaneous Adverse Drug Reactions Induced by Amlodipine.

Amlodipine-induced hypersensitivity reaction mimicking CD30+ mycosis fungoides

“…The cutaneous manifestations of pseudolymphoma induced by amlodipine range from diffuse desquamated erythema to more focal papules and annular plaques. 6 , 7 The diagnosis for our patient was more consistent with a drug-induced pseudolymphoma rather than a nonspecific drug hypersensitivity syndrome. Histologic examination found features of cutaneous T-cell lymphoma, and the cutaneous reaction resolved once the drug was stopped.…”

Amlodipine-Induced Eczematous Drug Eruption

“…Flushing, a nonallergic process, is the most common cutaneous adverse effect; urticaria and an erythematous maculopapular rash are the most common allergic reactions. 9 Although CCB-induced cutaneous adverse drug reactions have been studied, most studies are limited to a few case reports. One study was conducted between January 2004 and December 2010 in Thailand and showed that out of 996,583 CCB prescriptions, only 46 patients had developed cutaneous adverse drug reactions, with maculopapular rash being the most common dermatologic manifestation at 41.7%.…”