Cutaneous involvement by Burkitt lymphoma

Jacobson, Michael A.; Hutcheson, Angela C. S.; Hurray, David H.; Metcalf, John S.; Thiers, B.H.

doi:10.1016/j.jaad.2006.02.030

Cited by 27 publications

(18 citation statements)

References 5 publications

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“…However, satellite lesions and regional metastasis not directly communicating with the main tumor have also been reported in an area distal to the previous surgical field. [10] Similarly, in our case, the site of the nodule was distant from the site of surgery. Recently, a case of gastric DLBCL with cutaneous involvement has also been reported.…”

Section: Discussionsupporting

confidence: 62%

“…[9] Unlike adult patients in whom stomach is the most frequent site, small and large intestines are the most commonly involved sites in pediatric age group. [10] Five out of six patients in the present study had involvement of small intestine with colonic involvement in only one case. The male to female ratio of childhood GI NHL is reported to be from 7:1 to 1.8–2.5: 1.…”

Section: Discussionmentioning

confidence: 67%

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Primary pediatric gastrointestinal lymphoma

Bandyopadhyay

Sinha

Chatterjee

et al. 2011

Indian Journal of Medical and Paediatric Oncology

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Background:Primary non-Hodgkin's lymphoma (NHL) of the gastrointestinal (GI) tract is the most common extranodal lymphoma in pediatric age group. Yet, the overall incidence is very low. The rarity of the disease as well as variable clinical presentation prevents early detection when the possibility of cure exists.Materials and Methods:We studied six cases of primary GI NHL in pediatric age group with reference to their clinical presentation, anatomic distribution and histopathologic characteristics.Results:All were males except one. Intestinal obstruction was the presenting feature in 50%. Half the cases showed ileocaecal involvement, while large bowel was involved in 16%. Histology showed four cases of diffuse large B-cell lymphoma (DLBCL), one case of Burkitt lymphoma, and one Burkitt-like lymphoma. Immunohistochemistry for Tdt, CD20, CD3, CD30, bcl2, bcl6 confirmed the morphological diagnosis.Conclusion:Pediatric GI lymphoma commonly involves the ileocaecal region and presents with intestinal obstruction. A higher prevalence of DLBCL is found compared to other series. A high proliferative index is useful in differentiating Burkitt-like lymphoma from DLBCL.

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Section: Discussionsupporting

confidence: 62%

Section: Discussionmentioning

confidence: 67%

Primary pediatric gastrointestinal lymphoma

Bandyopadhyay

Sinha

Chatterjee

et al. 2011

Indian Journal of Medical and Paediatric Oncology

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“…This paper is a case of primary skin or soft tissue involvement of the chest wall in the absence of apparent nodal mass or visceral disease as the initial manifestation of BL. While there are isolated reports of skin and soft tissue involvement by BL, these cases were in the setting of immunodeficiency state and were felt to be the result of either iatrogenic tumor seeding after nodal biopsies [5, 6], for which there is limited prospective evidence of such a mechanism, or local spread from intrathoracic lymph nodes in the setting of recurrent disease [6, 7]. Cases of BL arising in soft tissue of the lower extremity and chest wall during relapse in a child have also been reported [8, 9].…”

Section: Discussionmentioning

confidence: 99%

Primary Burkitt Lymphoma of the Chest Wall

2012

Case Reports in Hematology

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Burkitt lymphoma (BL) originating in the skin and soft tissue at any site is exceedingly rare. This paper is about a case of primary sporadic BL that presented as an isolated, rapidly enlarging chest wall mass arising from skin and/or soft tissue in an adult. As with other BL presentations, this patient was treated with aggressive chemotherapy with central nervous system (CNS) chemoprophylaxis, but he later died because of sepsis.

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“…This paper is a case of primary skin or soft tissue involvement of the chest wall in the absence of apparent nodal mass or visceral disease as the initial manifestation of BL. While there are isolated reports of skin and soft tissue involvement by BL, these cases were in the setting of immunodeficiency state and were felt to be the result of either iatrogenic tumor seeding after nodal biopsies [5,6], for which there is limited Case Reports in Hematology prospective evidence of such a mechanism, or local spread from intrathoracic lymph nodes in the setting of recurrent disease [6,7]. Cases of BL arising in soft tissue of the lower extremity and chest wall during relapse in a child have also been reported [8,9].…”

Section: Discussionmentioning

confidence: 99%