Cutaneous metastases: Where do they come from and what can they mimic?

Leonard, N.

doi:10.1016/j.cdip.2007.05.011

Cited by 21 publications

(27 citation statements)

References 48 publications

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“…In the present 52 study, breast cancer was also the most common site of primary tumor. Cutaneous metastasis may occur by direct extension, local invasion through lymphatics/body cavities, or distant metastasis via the hematogenous or lymphatic route [9][10][11][12] . The complex molecular mechanisms responsible for tumoral metastasis to the skin are not completely understood.…”

Section: Discussionmentioning

confidence: 99%

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Cutaneous Metastasis: A Study of 138 Cases Diagnosed by Fine-Needle Aspiration Cytology

Handa¹,

Kundu²,

Dimri

2016

Acta Cytologica

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Background: Cutaneous metastases can occur in a wide variety of internal malignancies and may be the first sign of a clinically silent visceral cancer. Study Design: A retrospective analysis was made of 138 cases diagnosed with cutaneous and subcutaneous metastasis on fine-needle aspiration cytology (FNAC). Primary tumors of the skin/subcutis were excluded. Results: Of 138 cases, the primary was known in 101 cases and unknown in 37 cases. The age of the patients ranged from 5 to 86 years, and 76 (55.1%) were male and 62 (44.9%) were female. Clinically, the most common lesion was a single nodule (n = 77, 55.8%). The chest wall was the predominant site (n = 53, 38.4%). In males and females, the most common primary sites were the lung (n = 16) and breast (n = 24), respectively. On cytology, the most common diagnosis was metastatic adenocarcinoma (n = 41, 29.7%). Of 37 cases with an unknown primary, FNAC helped to locate the primary site in 17 (45.9%) cases, while in 20 cases it remained undiagnosed. Conclusions: FNAC is a rapid and safe technique that can be used as a first line of investigation for confirmation of metastatic lesions of the skin. Critical evaluation of cytomorphological features along with relevant clinical details could help in the localization of an unknown primary site in some cases.

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Section: Discussionmentioning

confidence: 99%

“…In this group the most common site for a cutaneous metastasis was the chest wall (12) followed closely by the abdominal wall (9). Multiple-site involvement was seen in 5 cases.…”

Section: Cases With Unknown Primary Tumormentioning

confidence: 94%

Cutaneous Metastasis: A Study of 138 Cases Diagnosed by Fine-Needle Aspiration Cytology

Handa¹,

Kundu²,

Dimri

2016

Acta Cytologica

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“…This surgery is quite illusory, the prognosis is essentially to the voluminous left frontoparieto-occipital mass. The evolution of these skin lesions is to necrotic ulcerations with frequents super infections [7,8]. The erosion of the underlying bone is possible, but is discrete and sometimes non-obvious during morphological examination [7][8][9][10][11].…”

Section: Biological Examinations and Resultsmentioning

confidence: 99%

An Exceptional Case of Cutaneous Metastasis of Differentiated Thyroid Cancer

Vaudrey¹,

Im²,

Nr³

et al. 2015

Endocrinol Metab Syndr

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Cutaneous metastasis from thyroid carcinoma is rare. It's often combined with other metastasis exceptionally isolated. We report the case of a 60 year-old patient operated in 2008 with thyroid surgery without a surgery report and an anatomo-pathological examination. She presents a huge scalp lesion with bone lysis visible with MRI and scanner. Samples confirmed the metastasis of a follicular thyroid cancer.

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“…But the most common presentation is smooth, firm non-tender nodules, which appears in 80% of the cases (27). The scalp and umbilicus (Sister Mary Joseph nodule) are the most common sites for metastases, although any sites can be involved (31). Regarding the histopathology, cutaneous metastasis usually shares features of the primary tumor but may be more undifferentiated (30).…”

Section: Epidemiologymentioning

confidence: 99%

Lung Sarcomatoid Carcinoma Metastasis to Skin: A Case Report and Review of the Literature

Lin

Wang

et al. 2016

Cancer Investigation

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Sarcomatoid carcinoma is a biphasic neoplasm composed of highly complex, intimately admixed malignant epithelial and mesenchymal elements. We herein report a rare case of cutaneous metastasis of pulmonary sarcomatoid carcinoma that contains liposarcomatous, rhabdosarcomatous and chondrosarcomatous heterologous differentiation, and review relevant literatures to lead to a better understanding of this rare but highly aggressive tumor.

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Cutaneous metastases: Where do they come from and what can they mimic?

Cited by 21 publications

References 48 publications

Cutaneous Metastasis: A Study of 138 Cases Diagnosed by Fine-Needle Aspiration Cytology

Cutaneous Metastasis: A Study of 138 Cases Diagnosed by Fine-Needle Aspiration Cytology

An Exceptional Case of Cutaneous Metastasis of Differentiated Thyroid Cancer

Lung Sarcomatoid Carcinoma Metastasis to Skin: A Case Report and Review of the Literature

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