Acne vulgaris is a non-infectious, inflammatory disorder that localizes to the sebaceous gland-rich parts of the body such as the face, the back and the chest, affecting the majority of adolescents and young adults worldwide. [1][2][3] Although it is the disease of the pilosebaceous unit, acne may involve the interfollicular regions as well, reflected by the clinical findings where inflammation exceeds the openings of the follicules already in the mild forms of acne. 4 Furthermore, a characteristic feature of acne is increased sebum production, providing a unique setting wherein inflammation is not linked to skin dryness but