Cyclic loading (vibration) accelerates tooth movement in orthodontic patients: A double-blind, randomized controlled trial

Pavlin, Dubravko; Anthony, Ravikumar; Raj, Vishnu; Gakunga, Peter T.

doi:10.1053/j.sodo.2015.06.005

Cited by 103 publications

(126 citation statements)

References 33 publications

(27 reference statements)

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“…31 There is currently data from retrospective studies and two randomized clinical trials showing evidence of increased rates of tooth movement and reduced pain when using fixed appliances combined with supplemental vibrational force. [32][33][34] However, retrospective studies are known to be associated with bias and an exaggeration of treatment effects, 35 whilst both the existing randomized trials are at risk of bias. 36 Indeed, advertisement claims and the promising results of the early pilot studies have not been confirmed by subsequent well-designed randomized clinical trials that have shown no improvement in either tooth alignment rates or pain experience associated with supplemental vibrational force.…”

Section: Introduction Backgroundmentioning

confidence: 99%

Effect of supplemental vibrational force on orthodontically induced inflammatory root resorption: A multicenter randomized clinical trial

DiBiase

Woodhouse

Papageorgiou

et al. 2016

American Journal of Orthodontics and Dentofacial Orthopedics

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INTRODUCTION A multicenter parallel 3-arm randomized clinical trial was carried out in 1 university and 2 district hospitals in the United Kingdom to investigate the effect of supplemental vibrational force on orthodontically induced inflammatory root resorption (OIIRR) during the alignment phase of fixed appliance therapy. METHODS Eighty-one subjects less than 20 years old with mandibular incisor irregularity undergoing extraction-based fixed-appliance treatment were randomly allocated to supplementary (20 minutes a day) use of an intraoral vibrational device (AcceleDent; OrthoAccel Technologies, Houston, Tex) (n = 29), an identical nonfunctional (sham) device (n = 25), or fixed appliances only (n = 27). OIIRR was measured blindly from long-cone periapical radiographs of the maxillary right central incisor taken at the start of treatment and the end of alignment when a 0.019 × 0.025-in stainless steel archwire was placed (mean follow-up, 201.6 days; 95% confidence interval [CI], 188.6-214.6 days). Data were analyzed blindly on a per-protocol basis because losses to follow-up were minimal, with descriptive statistics, 1-way analysis of variance, and univariable and multivariable regression modeling. RESULTS Nine patients were excluded from the analysis; they were evenly distributed across the groups. Mean overall OIIRR measured among the 72 patients was 1.08 mm (95% CI, 0.89-1.27 mm). Multivariable regression indicated no significant difference in OIIRR for the AcceleDent (difference, 0.22 mm; 95% CI, -0.14-0.72; P = 0.184) and AcceleDent sham groups (difference, 0.29 mm; 95% CI, -0.15-0.99; P = 0.147) compared with the fixed-appliance-only group, after accounting for patient sex, age, malocclusion, extraction pattern, alignment time, maximum pain experienced, history of dentoalveolar trauma, and initial root length of the maxillary right central incisor. No other side-effects were recorded apart from pain and OIIRR. CONCLUSIONS The use of supplemental vibrational force during the alignment phase of fixed appliance orthodontic treatment does not affect OIIRR associated with the maxillary central incisor. REGISTRATION ClinicalTrials.gov (NCT02314975). PROTOCOL The protocol was not published before trial commencement. FUNDING Functional and sham AcceleDent units were donated by the manufacturer; there was no contribution to the conduct or the writing of this study.

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Section: Introduction Backgroundmentioning

confidence: 99%

Effect of supplemental vibrational force on orthodontically induced inflammatory root resorption: A multicenter randomized clinical trial

DiBiase

Woodhouse

Papageorgiou

et al. 2016

American Journal of Orthodontics and Dentofacial Orthopedics

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“…Similarly, Woodhouse et al found no evidence that supplemental vibrational force can increase the rate of initial tooth movement or reduce the amount of time required to achieve final alignment when used in conjunction with a preadjusted conventional appliance (15). Contrary to these findings, Pavlin et al (19) reported that low-level cycling loading of 0.25N at 30 Hz released by the same vibrational appliance used in the study of Miles et al increases the rate of orthodontic tooth movement (OTM) when applied as adjunct to orthodontic treatment. In a recent study Leethankul et al investigated through a split-mouth study the levels of IL-1β in gingival cervicular fluid and the rate of orthodontic tooth movement in canines stimulated by electric toothbrush compared to standard orthodontic movement of canines (16).…”

Section: Ivyspring International Publishermentioning

confidence: 46%

Aligning Effectiveness, Secretion of Interleukin 1β and Pain Control During Fixed Orthodontic Treatment with Self-Ligating Appliances and Supplemental Vibrational Appliances. A Randomized Controlled Clinical Trial

Kalemaj¹,

Buti²,

Deregibus³

et al. 2017

J. Biomed

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Aims: The aims of the present study were to investigate rate of mandibular incisors alignment, levels of IL-1β and pain and discomfort during orthodontic alignment with the following: 1) conventional-ligating appliance (CLA); 2) self-ligating appliance (SLA); 3) self-ligating appliance combined to vibrational appliance (SLA-VA). Methods: This was a three-armed parallel group randomized clinical trial with allocation ratio 1:1:1. The main inclusion criteria were: full permanent dentition, age below 25 years, no missing teeth, first skeletal and molar class, non-extraction treatment, Little's Irregularity Index (LII) from 3mm to 6mm. The main outcomes were rate of mandibular incisors alignment, concentration of IL-1β and pain and discomfort. Measurements on models were performed at appliance placement (t0) and at monthly intervals for the first 3 months (T1, T2, T3), whereas IL-1β levels were measured at weekly intervals for the first 3 weeks (t1, t2, t3). Differences between groups for normally-distributed variables were initially estimated through Analyses of Variance (ANOVAs) tests, followed by Post-Hoc Scheffe analysis for pair wise comparisons. Results: Thirty-three patients were recruited and randomized with no lost to follow-up. During the first two months, faster alignment was observed for SLA (P=0.0491) and SLA-VA (P=0.0134) compared to CLA. At each time-point of measurement no differences were observed between SLA and SLA-VA. At t1 and t2 were found higher values of IL-1β for SLA-VA compared to SLA (P=0.0209, P=0.0352) and CLA (P=0.0018, P=0.0029), whereas at t3 the difference persisted only versus CLA (P=0.0304). No relevant differences in terms of pain and discomfort were observed between groups at any time point. Conclusions: Self-ligating appliances seem to perform better than conventional-ligating appliances in terms of timing of teeth leveling and alignment. Vibrational devices seem to enhance secretion of IL-1β but do not increase effectiveness of leveling and alignment with regard to treatment acceleration or pain reduction.

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“…Dubravko et al used the AcceleDent device (OrthoAccel Technologies, Inc., Bellaire, USA) to generate a vibration of 0.25 N and a frequency of 30 Hz. 54 It was possible to accelerate the distalization of canines with skeletal anchorage by 48.1% compared to the control group (1.16 mm vs 0.79 mm/month). Other reports have also confirmed the accelerating effect of vibrations.…”

Section: Vibrationsmentioning

confidence: 96%

Methods of accelerating orthodontic tooth movement: A review of contemporary literature

Kacprzak¹,

Strzecki²

2018

Dent. Med. Probl.

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Technological progress and the introduction of modern therapeutic methods are constantly changing contemporary orthodontics. More and more orthodontic patients are working adults, who expect satisfactory therapeutic effects as soon as possible, increasing the importance of methods accelerating tooth movement. The aim of this study was to review the current literature regarding methods of accelerating tooth movement and reducing the duration of the active phase of therapy. The literature was collected from the PubMed and EBSCO databases using "accelerated orthodontic tooth movement" as the search key words. The methods described were categorized as conservative and surgical. The pharmacological agents used in conservative treatment, such as growth hormone, parathyroid hormone, thyroxine, and vitamin D, are especially worth mentioning. They stimulate osteoclasts to increase resorption through a variety of mechanisms. Effective methods also include physical stimuli, e.g., vibrations or photobiomodulation. Most studies describing the effects of pharmacological agents were based on animal subjects and they may therefore lack clinical relevancy. Corticotomy and its modifications based on the regional acceleratory phenomenon (RAP) might prove to be a useful augmentation of orthodontic treatment, especially in adults, including patients with periodontal disease.

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Cyclic loading (vibration) accelerates tooth movement in orthodontic patients: A double-blind, randomized controlled trial

Abstract: Keywords -Accelerated orthodontic tooth movement; Effect of vibrations on tooth movement; Effect of vibrations on bone; Cyclic loading and tooth movement; AcceleDent and tooth movement.

Cited by 103 publications

References 33 publications

Effect of supplemental vibrational force on orthodontically induced inflammatory root resorption: A multicenter randomized clinical trial

Effect of supplemental vibrational force on orthodontically induced inflammatory root resorption: A multicenter randomized clinical trial

Aligning Effectiveness, Secretion of Interleukin 1β and Pain Control During Fixed Orthodontic Treatment with Self-Ligating Appliances and Supplemental Vibrational Appliances. A Randomized Controlled Clinical Trial

Methods of accelerating orthodontic tooth movement: A review of contemporary literature

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