CYTOLOGY OF A GENETIC SEXING SYSTEM IN <i>ANOPHELES ALBIMANUS</i>

Kaiser, P. E.; Seawright, J. A.; Joslyn, D. J.

doi:10.1139/g79-024

Cited by 25 publications

(15 citation statements)

References 5 publications

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“…arabiensis in El Salvador. 31,59 However, modern genetics provides more options and also allows such systems to be transferred more readily from one species to another. Several have been developed.…”

Section: Large-scale Separation Of Males and Femalesgenetic Sexing Stmentioning

confidence: 99%

Genetic control ofAedesmosquitoes

Alphey

McKemey

Nimmo

et al. 2013

Pathogens and Global Health

134

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Aedes mosquitoes include important vector species such as Aedes aegypti, the major vector of dengue. Genetic control methods are being developed for several of these species, stimulated by an urgent need owing to the poor effectiveness of current methods combined with an increase in chemical pesticide resistance. In this review we discuss the various genetic strategies that have been proposed, their present status, and future prospects. We focus particularly on those methods that are already being tested in the field, including RIDL and Wolbachia-based approaches.

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Section: Large-scale Separation Of Males and Femalesgenetic Sexing Stmentioning

confidence: 99%

Genetic control ofAedesmosquitoes

Alphey

McKemey

Nimmo

et al. 2013

Pathogens and Global Health

134

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“…Without informed management, this loss of linkage of insecticide resistance with the Y chromosome would gradually result in an increase in recombinant resistant females and susceptible males. It was necessary to purge the recombinants and replace the stock at regular intervals despite the stabilizing inversion that had been incorporated into the strain [27]. …”

Section: Factors Critical To the Deployment Of Sterile Male Mosquitoesmentioning

confidence: 99%

Historical applications of induced sterilisation in field populations of mosquitoes

Dame

Curtis

Benedict

et al. 2009

Malar J

156

146

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Research on sterile mosquito technology from 1955 to the 1980s provided a substantial body of knowledge on propagation and release of sterile mosquitoes. Radiation sterilisation and chemosterilisation have been used effectively to induce dominant lethality and thereby sterilise important mosquito vectors in the laboratory. Experimental releases of chemosterilised males provided complete control of Anopheles albimanus in a small breeding population (14-15 sq km) in El Salvador. Releases of radiation sterilised males failed to control either Aedes aegypti or Anopheles quadrimaculatus in the USA. Releases of radiation-sterilised and chemosterilised male Culex quinquefasciatus in the USA and India were successful in some instances. Development of genetic sexing systems for Anopheles and improved physical separation methods for Culex have made it possible to rear and release males almost exclusively (> 99%) minimizing the release of potential vectors, the females. Factors that affected efficacy in some field programmes included reduction of competitiveness by radiation, immigration of fertilized females from outside the release zones, and inability of laboratory-bred males to perform in the wild. Despite significant progress, institutional commitments to carry the process further were generally lacking in the late 1970s and until recently. Now, with renewed interest and support for further assessment of this technology, this paper summarizes the current knowledge base, prioritizes some areas of investigation, and challenges scientists and administrators to maintain an awareness of progress, remain realistic about the interpretation of new findings, and make decisions about the sterile insect technique on the basis of informed scientific documentation. Areas recommended for priority research status include the establishment of genetic sexing mechanisms that can be transferred to other mosquito species, re-examination of radiation sterilisation, aerial release technology and mass rearing.

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“…In such strains, genetic markers indicate the presence of the chromosomal aberrations through either altered linkage relationships or position effects of genes located close to chromosomal breakpoints. Genetic markers such as w and y also can be used in monitoring the production and maintenance of genetic sexing systems (Curtis et al, 1976;Kaiser et al, 1978;Shetty, 1987;Baker et al, 1981;Weller & Foster, 1993). More fundamentally, such genetic markers are necessary for expanding the linkage maps being established for An.…”

Section: Discussionmentioning

confidence: 99%