Daun Mangga (Mangifera indica L): Potensi Baru Penyembuh Luka Sayat

Risa, Arista Mutiara; Pantiwati, Yuni; Mahmudati, Nurul; Husamah, Husamah; Miharja, Fuad Jaya

doi:10.20414/jb.v11i2.128

Cited by 7 publications

(9 citation statements)

References 3 publications

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“…Based on research by Permatasari et al (2018), mango leaf extract of Cengkir cultivar can reduce blood glucose levels in fructose-induced mice, with an optimal dose 105 mg/kg/BW. Risa et al (2018) also proved that there was a significant effect on given mango leaf extract of Manalagi cultivar on wound healing in mice with optimal concentration 20%. This is also supported by Ayuningtyas (2020) that states a mixture of honey and dried mango leaf powder can assist wound healing.…”

Section: Introductionmentioning

confidence: 78%

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Effect of Mango Leaf Shoot Extract (Mangifera indica L.) on Zebrafish (Danio rerio) Cell Regeneration Induced by Hyperglicemia

2022

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Abstract. In many cases, diabetics often have difficulty in wound healing and lead to amputation. Hyperglycemia is an early symptom of diabetic which is characterized by high blood glucose levels. Cell regeneration is one of part by wound healing process. Mango plants have benefits as medicinal plants because they have secondary metabolites that can help heal wounds. The purpose of this study was to determine the effect of mango leaf shoot extract on blood glucose levels of zebrafish (Danio rerio) hyperglycemia due to alloxan and glucose induction and role of mango leaf shoot extract on zebrafish caudal fin regeneration. This study used an experimental method with 5 group treatments: control group, hyperglycemia, metformin 0,75 w/v, extract 10 µg/ml and extract 20 µg/ml. Parameters observed include blood glucose level, fin length and survival rate. Hyperglycemia was measured by blood glucose level, caudal fin regeneration was analayzed using fin length, also environmental factors and survival rate were measured. Result showed that mango leaf shoot extract 20 µg/ml was efective in reducing blood glucose levels, reaching 68,31% and aproaching metformin 0,75 w/v treatment with a decrease in blood glucose levels reaching 70,1%. Mango leaf shoot extract with concentration 20 µg/ml significantly different (p < 0,05) from hyperglycemia group and extract 10 µg/ml. Extract 20 µg/ml was effective in assisting the regeneration process with an increase caudal fin length reaching 0.94 cm during the treatment period.

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Section: Introductionmentioning

confidence: 78%

“…Mango plant has benefits as a medicinal plant and has been widely used as traditional medicine (Luqyana & Husni, 2019). Mango plants have potential to help wound healing process of diabetics (Risa et al, 2018). In Indonesia, mango leaf shoot are consumed as salad.…”

Section: Introductionmentioning

confidence: 99%

Effect of Mango Leaf Shoot Extract (Mangifera indica L.) on Zebrafish (Danio rerio) Cell Regeneration Induced by Hyperglicemia

2022

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“…Pada masyarakat di India, daun mangga (Mangifera indica) digunakan sebagai salah satu obat untuk menyembuhkan luka bakar (Bailung & Puzari, 2016). Mangga memiliki senyawa seperti saponin, tannin, dan flavonoid yang dapat menyembuhkan luka (Risa, Pantiwati, Mahmudati, Husamah, & Miharja, 2018).…”

Section: Pendahuluanunclassified

Penggunaan Madu dan Mangga (Mangifera indica) pada Penyembuhan Luka

Ayuningtyas

2020

JHSP

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Penggunaan obat-obatan tradisional seperti tanaman sudah dilakukan secara turun temurun untuk menyembuhkan berbagai penyakit. Salah satunya adalah penggunaan mangga (Mangifera indica) dan madu sebagai obat untuk menyembuhkan luka. Madu dengan komponen antimicrobial dan antioksidan yang mampu menyembuhkan luka. Madu juga dapat memberikan efek lapisan protektif dan menjaga kelembaban sehingga bakteri tidak dapat berkembang. Mangga mengandung mangiferin yang merupakan komponen yang dapat menyembuhkan luka dengan adanya vitamin A dan vitamin C yang penting dalam proses pembentukan kolagen dan jaringan ikat sehingga terjadi penyembuhan luka. Penggunaan campuran madu dan mangga diketahui dapat mempercepat proses penyembuhan luka dibandingkan jika digunakan secara terpisah

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“…Berbeda dengan kelompok kontrol positif yang menggunakan povidone iodine sebagai pembanding yang juga dapat mempercepat penyembuhan luka. Mekanisme kerja povidone iodine bekerja setelah kontak langsung dengan jaringan, elemen iodine akan dilepaskan secara perlahan dengan cara menghambat metabolisme enzim bakteri sehingga mengganggu multiplikasi bakteri dan menjadi lemah (20) . Kontrol negatif yaitu kelompok kontrol yang tidak diberikan perlakuan apapun atau tidak diberikan zat aktif yang dapat mempercepat penyembuhan luka, maka dari itu pemulihan luka berlangsung lama, sehingga penyembuhan luka terjadi secara alami, dimana penyembuhan akan terjadi sesuai proses fisiologis tubuh mencit (20) .…”

Section: Gambar 1 Grafik Persentase Penyembuhanunclassified

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Dewi¹,

Verawaty²,

Taslim³

2020

j. ilm. manuntung sains farm. kesehat.

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This study was conducted to determine the effectiveness of garlic (Allium sativum L.) extract gel for healing burns and cuts. Garlics are often used in healing wound because they contained sulfur in garlic, namely Diallyl thiosulfinate (allicin) and Diallyl disulfide (ajoene). Allicin in garlic will reduce inflammatory reactions and antibacterial, which will accelerate in healing wound. Garlics extract made in gel preparations with a concentration of 15% and 20%, then given to burns and cuts mice that have been divided into several groups. In testing, mice that had been made burns were divided into 4 groups and each group contain of 3 mice, namely the 15%, 20% concentration gel group. The Bioplacenton group as a comparison and also the control group. In the examination of cuts, the division of the group of mice that have been made the cuts is the same as the burn test, the comparison is Povidone iodine. From the burn test, the results are the 20% concentration gel group experienced the best healing after 18 days of gel administration and its healing power was better than Bioplacenton. The results of cuts testing is the 15% concentration gel group experienced the best healing and slightly better than Povidone Iodine.

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Daun Mangga (Mangifera indica L): Potensi Baru Penyembuh Luka Sayat

Cited by 7 publications

References 3 publications

Effect of Mango Leaf Shoot Extract (Mangifera indica L.) on Zebrafish (Danio rerio) Cell Regeneration Induced by Hyperglicemia

Effect of Mango Leaf Shoot Extract (Mangifera indica L.) on Zebrafish (Danio rerio) Cell Regeneration Induced by Hyperglicemia

Penggunaan Madu dan Mangga (Mangifera indica) pada Penyembuhan Luka

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