Today, with the development of industry and mechanized life style, the prevalence of the disease is rising steadily as well. Observing at the trend and lifecycle style, its predict that after ten years around 23.6 million people die because of Cardiovascular Disease (CVD). For that reason, aim to use Deep Learning Techniques (DLTs), to analysis stable CVD that would give valuable awareness to decrease misdiagnosis in the Robust Healthcare Industry (RHI). An objective of this paper is first, Molecular diagnosis (MD), and second using Deep Learning Techniques DLTs, to synthesis and characterize to accumulate (raw information) from CVD patients, those who admitted the emergency section between January (2018 to December 2019). We are using Artificial Neural Network (ANN), model characterize to predict CVD patients and configuration, Feature selection (FS), Mean Square Error (MSE), accuracy, sensitivity. The ANN accuracy is 98.4, K-nearest neighbor (KNN) accuracy is 98.01%, Naïve Bayes (NB), accuracy is 96.99%. Decision tree (DT), accuracy is 87.81%. Our robust data driven model explore the efficient accuracy rate to predict CVD patients. The ANN model in term of their efficient in disease analysis, and prognosis of the RHI. INDEX TERMS Artificial neural network (ANN), cardiovascular disease (CVD), molecular diagnostic (MD), Robust Healthcare Industry (RHI).