Definition, prevalence and development of nasal obstruction

Jessen, Max; Malrn, Lars

doi:10.1111/j.1398-9995.1997.tb04876.x

Cited by 117 publications

(89 citation statements)

References 11 publications

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“…The incidence of allergic rhinitis from 1992 to 2000 was 4.8%, while 23.1% of the cases with allergic rhinitis in 1992 stated no rhinitis symptoms in 2000 indicating remission. After a 10-y course of the disease, 20% of patients with nonallergic rhinitis reported spontaneous disappearance and 36% improvement (861).…”

Section: Natural Historymentioning

confidence: 99%

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Bousquet¹,

Khaltaev²,

Cruz³

et al. 2008

Allergy

3,867

1,761

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Section: Natural Historymentioning

confidence: 99%

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Bousquet¹,

Khaltaev²,

Cruz³

et al. 2008

Allergy

3,867

1,761

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“…Perhaps because of the multitude of causes that can give rise to a subjective sensation or objective presence of nasal airway restriction many different synonyms are used in literature, apparently without a uniform definition. Common synonyms are nasal obstruction, nasal stuffiness, nasal congestion, and nasal blockage (2).…”

mentioning

confidence: 99%

Evidence‐based recommendations regarding the differential diagnosis and assessment of nasal congestion: using the new GRADE system

Spronsen

Ingels

Jansen

et al. 2008

Allergy

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Nasal congestion is an important symptom in nasal pathology and can be defined as an objective restriction of nasal cavity airflow because of mucosal pathology and/or increased mucus secretion (excluding anatomical variants). Using the new Grading Recommendations Assessment, Development and Evaluation system, evidence‐based recommendations are made that will encompass different clinical questions regarding diagnostic modalities of nasal congestion: (i) their usefulness in assessment of presence and severity of congestion; (ii) their usefulness in assessment of etiological pathology responsible for congestion; and (iii) their usefulness in follow up and treatment effectiveness evaluation of nasal congestion.

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“…After the exclusion of common cold, rhinitis can be classified either as allergic or nonallergic, noninfectious (1). The last category of rhinitis usually includes rhinitis of both known and unknown origins (1,20).…”

Section: Discussionmentioning

confidence: 99%

Monosodium benzoate hypersensitivity in subjects with persistent rhinitis

Pacor

Lorenzo

Martinelli

et al. 2004

Allergy

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Background: Very few data are available from the literature on whether nonatopic subjects affected by persistent rhinitis may show the appearance of objective symptoms of rhinitis after the ingestion of food additives such as tartrazine (E102), erythrosine (E127), monosodium benzoate (E211), p‐hydroxybenzoate (E218), sodium metabisulphite (E223), and monosodium glutamate (E620). It is still unclear whether the ingestion of food additive may cause, as well, a consensual reduction of nasal peak inspiratory flow (NPIFR). Therefore, we used a double‐blind placebo‐controlled (DBPC) study to evaluate this hypothesis.Patients and methods: Two hundred and twenty‐six consecutive patients (76 males and 150 females) aged 12–60 years (mean age 40.2 ± 16.3 years). After 1 month of an additive‐free diet regimen, an open challenge was carried out (food additive‐rich diet for 2 weeks). After this period, challenges were administered in a DBPC manner using the above‐mentioned substances under investigation.Results: Twenty of 226 subjects (8.8%) reported an improvement of the symptoms of rhinitis after additive‐free diet. More precisely, six of 226 (2.6%) were symptom‐free and 14 of 226 (6.2%) showed an improvement in their symptoms after an additive‐free diet. As far as the results for DBPC are concerned, 20 challenges with monosodium benzoate induced both objective (i.e. sneezing and rhinorrhoea) and subjective symptoms (nasal blockage and nasal itching) of rhinitis with reduction of NPIFR ≥20%, 45 challenges induced subjective symptoms of rhinitis (i.e. nasal blockage and nasal itching), without reduction of NPIFR ≥20% of the basal value, two with tartrazine, seven with erythrosine, 19 with monosodium benzoate, three with p‐hydroxybenzoate, six with sodium metabisulphite, and eight with monosodium glutamate, respectively.Conclusions: The observation that nonatopic persistent rhinitis may be caused by the frequent, probably daily, ingestion of small doses of a nontolerated substance is intriguing and suggests that at least some patients with ‘chronic vasomotor rhinitis’ may be intolerant to a particular food additive. Therefore, food additives can be considered triggers or aggravating factors, rather than aetiological factors.

show abstract

Definition, prevalence and development of nasal obstruction

Cited by 117 publications

References 11 publications

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Evidence‐based recommendations regarding the differential diagnosis and assessment of nasal congestion: using the new GRADE system

Monosodium benzoate hypersensitivity in subjects with persistent rhinitis

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