Degradation Behavior of Calcium Sulfate/β-Tricalcium Phosphate Composites in Tris

Poly(propylene fumarate)/(calcium sulphate/β-tricalcium phosphate) composites: Preparation, characterization and in vitro degradation

“…This demonstrates that degradation clearly occurred in CaSO 4 /b-TCP granules, and that the degradation rate was higher than that of PPF/NVP matrix. This can be attributed to the fact that the degradation rate of CaSO 4 is much faster than that of b-TCP, which would leave pores ($5 lm) in the material and thereby accelerate the degradation of b-TCP [14]. In the last stages, HA and a small amount of CaSO 4 Á2H 2 O precipitated onto the CaSO 4 /b-TCP granules.…”

“…It is known that CaSO 4 degrades much faster than b-TCP, so a higher CaSO 4 /b-TCP ratio would induce a more rapid degradation of the CaSO 4 /b-TCP granules [14]. Thus the weight loss increased with increasing CaSO 4 /b-TCP molar ratio.…”

“…A CaSO 4 /b-TCP composite has been prepared in our laboratory, and the rate of its degradation can be adjusted by varying its composition and sintering temperature [14]. Therefore, filling a certain size of CaSO 4 /b-TCP spherical granules into PPF networks not only improves the mechanical property and biocompatibility of the composite, but also makes its degradation more controllable.…”