Dengue fever and insecticide resistance in Aedes mosquitoes in Southeast Asia: a review

Gan, Soon Jian; Leong, Yong Qi; Barhanuddin, Muhammad Fakrul Hakim bin; Wong, Siew Tung; Wong, Shew Fung; Mak, Joon Wah; Ahmad, Rohani

doi:10.1186/s13071-021-04785-4

Cited by 91 publications

(77 citation statements)

References 169 publications

(197 reference statements)

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“…Classical control measures, such as the application of an insecticide, have been capable of maintaining the population of these insects in check. Gradually, however, various insects gained resistance to these insecticides, thereby limiting the efficacy of control measures [4,5]. Apart from the limited efficacy, the environmental issues caused by insecticides and pest control agents constitute another emerging concern [6].…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition, Insecticidal and Mosquito Larvicidal Activities of Allspice (Pimenta dioica) Essential Oil

Narayanankutty¹,

Kuttithodi²,

Alfarhan

et al. 2021

Molecules

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Essential oils are biologically and environmentally safe pesticidal compounds yielded from aromatic plants. Spices are important sources of essential oils, and they are widely used in the medicine, food, and various other industries. Among the different spices, Allspice (Pimenta dioica) is underexplored in terms of its biological efficacy and a limited number of studies are available on the chemical composition of Allspice essential oil (AEO); thus, the present study evaluated the larvicidal property, the repellency, and the fumigant toxicity against common pests of stored products of AEO. AEO was found to inhibit the survival of larvae of such vectors as Aedis, Culex, and Armigeres species. Further, AEO was found to exert repellant effects against the pests of such stored products as Sitophilus, Callosobruchus, and Tribolium. Similarly, the fumigant toxicity was found to be high for AEO against these species. The contact toxicity of AEO was high against Sitophilus and Callosobruchus. Apart from that, the essential oil was found to be safe against a non-target organism (guppy fishes) and was found to be non-genotoxic in an Allium cepa model. Overall, the results of the present study indicate that the essential oil from Allspice could be used as an environmentally safe larvicidal and biopesticidal compound.

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Section: Introductionmentioning

confidence: 99%

Chemical Composition, Insecticidal and Mosquito Larvicidal Activities of Allspice (Pimenta dioica) Essential Oil

Narayanankutty¹,

Kuttithodi²,

Alfarhan

et al. 2021

Molecules

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“…gambiae has shown to be less affected by pyrethroids than the susceptible strain [58]. In the last few decades, kdr resistance mutations in different mosquito populations have expanded significantly which restricts pyrethroid usage in mosquito control [59]. Another target-site mutation, the AChE gene mutation (Ace-1R), causes resistance to organophosphates and carbamates.…”

Section: Insecticide Resistance In Mosquitoesmentioning

confidence: 99%

“…It is found that elevated levels of P450 activity resulted in pyrethroid resistant mosquito vectors [70][71][72][73][74]. Several CYPs are identified in mosquitoes and CYP overexpression is reported from insecticide resistant mosquito populations [45,59,[75][76][77]. Knockdown of the CYP through the RNA-interference technique also showed that mosquitoes become sensitive to pyrethroids [78][79][80].…”

Section: Insecticide Resistance In Mosquitoesmentioning

confidence: 99%

Plant-Based Bioinsecticides for Mosquito Control: Impact on Insecticide Resistance and Disease Transmission

Demirak

Canpolat

2022

Insects

105

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The use of synthetic insecticides has been a solution to reduce mosquito-borne disease transmission for decades. Currently, no single intervention is sufficient to reduce the global disease burden caused by mosquitoes. Problems associated with extensive usage of synthetic compounds have increased substantially which makes mosquito-borne disease elimination and prevention more difficult over the years. Thus, it is crucial that much safer and effective mosquito control strategies are developed. Natural compounds from plants have been efficiently used to fight insect pests for a long time. Plant-based bioinsecticides are now considered a much safer and less toxic alternative to synthetic compounds. Here, we discuss candidate plant-based compounds that show larvicidal, adulticidal, and repellent properties. Our discussion also includes their mode of action and potential impact in mosquito disease transmission and circumvention of resistance. This review improves our knowledge on plant-based bioinsecticides and the potential for the development of state-of-the-art mosquito control strategies.

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“…Along with adaptation to adverse climatic conditions, mosquitoes also face exposure to insecticides used by public health interventions for their control. Earlier studies have shown the susceptibility status of A. aegypti to insecticides 5 , but in recent years, resistance has been reported against major classes of insecticides from different parts of the country 6 as well as globally 7 . Biologically, two major mechanisms play a role in the development of insecticide resistance, i.e.…”

Section: Introductionmentioning

confidence: 99%

Untargeted metabolomics-based response analysis of temperature and insecticide exposure in Aedes aegypti

Singh

Kumar

Pande

et al. 2022

Sci Rep

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In this study, we utilized an untargeted NMR metabolomics approach to identify the vector response in terms of metabolic profiling after temperature and insecticide exposure in comparison with the control. Clearly, temperature and insecticide exposure cause changes in the underlying metabolism, and the NMR metabolomic profile enables a direct examination of the immediate response of the vector to cope up with these changes. The present study was designed in four parts: A-Aedes aegypti were exposed to 40 °C for one-hour, DDT-4%, malathion-5%, and deltamethrin-0.05% separately and, part B-D; one-hour exposure at 35 °C and 40 °C temperatures followed by one-hour exposure to insecticide. The resultant metabolite profiles were compared with the control. In response to temperature and insecticide exposure, several metabolites and altered pathways were identified. Citrate, maltose, lipids, Nicotinate, Choline, Pyruvate and β-hydroxybutyrate were found as important components of major biological pathways such as tri-carboxylic acid cycle, branched amino acid degradation, glycolysis/gluconeogenesis, amino acid metabolism, lipid and carbohydrate metabolism, nucleotide PRPP pathway, and phospholipid metabolism. Furthermore, the results also suggest that the changes imposed by exposure to temperature and insecticides individually, are reversed with combined exposure, thus negating the impact of each other and posing a threat to the control of Aedes-borne diseases such as dengue, chikungunya, Zika and yellow fever.

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Dengue fever and insecticide resistance in Aedes mosquitoes in Southeast Asia: a review

Cited by 91 publications

References 169 publications

Chemical Composition, Insecticidal and Mosquito Larvicidal Activities of Allspice (Pimenta dioica) Essential Oil

Chemical Composition, Insecticidal and Mosquito Larvicidal Activities of Allspice (Pimenta dioica) Essential Oil

Plant-Based Bioinsecticides for Mosquito Control: Impact on Insecticide Resistance and Disease Transmission

Untargeted metabolomics-based response analysis of temperature and insecticide exposure in Aedes aegypti

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