Dental Anomalies of the Permanent Lateral Incisors and Prevalence of Hypodontia outside the Cleft Area in Complete Unilateral Cleft Lip and Palate

Abstract

Objective To determine in complete unilateral cleft lip and palate (UCLP) subjects the characteristics (location, shape) of the cleft-side lateral incisor. The presence of a supernumerary tooth at the cleft side and the prevalence of hypodontia outside the cleft area were evaluated. A comparison was made of the shape of the cleft side lateral incisor to its contralateral incisor. Setting Hospital for Rehabilitation of Craniofacial Anomalies (HRCA), Sao Paulo, Brazil. Patients Orthopantomograms of 203 subjects with UCLP and without syndromes were chronologically selected from the HRCA data bank, within an age range of 5 to 10 years. Outcome Measure Orthopantomograms were analyzed by the same observer according to established criteria. Results There were no statistically significant differences between sexes for any of the criteria studied. The cleft-side lateral incisor was present in 50.2%, and it was more commonly located at the distal side (76.5%). The congenital absence of the cleft-side lateral incisor was observed in 49.8% of the sample, and its antimere was congenitally missing in 10.9%, this difference being statistically significant. The most commonly missing tooth outside the cleft area was the maxillary second premolar. Conclusions The high prevalence of hypodontia of the permanent lateral incisor in the cleft side showed that the cleft could play an important role in this absence. There were different patterns for the presence of the cleft-side lateral incisor.

Frequency of Different Dental Irregularities Associated With Cleft Lip and Palate in a Tertiary Care Dental Hospital

“…The difference in the prevalence of different missing teeth in the two studies indicate that two different set of genes might be altered differently in these two populations. Like other dental deformities mentioned earlier, it is reported that agenesis of teeth is more common near the cleft [21]. In this study there were 38% missing teeth (agenesis), 17% hypodontia (impacted), 8% anodontia (agenesis).…”

Dental Anomalies in Children Born with Clefts: A Case-Control Study

“…Usually the most absent teeth in individuals born with clefts are maxillary second premolars (Lourenço et al, 2003;Letra et al, 2007;.…”

FAT4 identified as a potential modifier of orofacial cleft laterality

“…OFCs lead to feeding difficulties and require multiple surgeries early in life to repair (Wehby & Cassell, 2010;Wehby et al, 2006). In addition to these early childhood complications, affected individuals are at a higher risk for dental (Akcam et al, 2010;Lourenco Ribeiro et al, 2003;Ribeiro et al, 2002) and speech problems (Jocelyn et al, 1996;Moll, 1968), ear infections (Jocelyn et al, 1996;Nackashi et al, 2002), various forms of cancer (Dietz et al, 2012;Menezes et al, 2009), and mental health concerns (Christensen & Mortensen, 2002), and these individuals have an overall higher rate of mortality across the life span (Christensen et al, 2004). Beyond its impact on health, individuals with OFCs also incur additional financial burdens, with the lifetime costs for cleft-related surgeries, hospital stays, orthodontic treatments, and speech therapy exceeding $200,000 (Wehby & Cassell, 2010;Wehby et al, 2006).…”