Dental implants in patients with osteogenesis imperfecta: a retrospective and prospective study with review of the literature

Abstract

Aim: The aims of the present study were to retrospectively examine Norwegian patients with osteogenesis imperfecta (OI) and dental implants, and to prospectively study a group of patients with OI in need of such treatment. Our hypothesis was that implant treatment in these patients has approximately the same success rate as in healthy persons. Study group: Seven patients with a diagnosis of OI and a total of 26 dental implants were invited to participate in the retrospective study. The prospective part of the study included a total of 20 implants in seven patients. Results: The patients in the retrospective study were seen after an average of 74 months after loading, range 25–135 months. Two implants had been lost, both of them before prosthetic loading and in the same patient. Bone loss of 4 mm or more was seen around three implants in two patients. The patients in the prospective study were followed for a mean observation time of 20 months after loading, range 12–33 months. No implants were lost in that group, and only minimal bone loss was observed (less than 1 mm around two implants in one patient). Conclusion: In these OI patients, the total implant survival rate was 95.7%, being 93.3% in the retrospective group and 100% in the prospective group, respectively.

Implant therapy for a patient with osteogenesis imperfecta type I: review of literature with a case report

“…Our patient is now 4 years post-placement of his first implant procedure and has been functioning without any issues. The diagnosis of OI type I should not be a contraindication of implant therapy as our case, and others [ 18 – 25 ], have shown. This case differs from other cases in utilizing synthetic grafts to aid in stability and providing another case to illustrate the advancements in implant delivery for patients with bone abnormalities.…”

“…In determining the success rate of dental implants, there is a great deal of variability due in part to the varying degrees of bone quality and quantity in the OI subtypes, patient compliance to treatment plans and dental care, and a multitude of other factors typically involved in implant therapy. One retrospective and prospective study cites strong success rates in implant delivery for OI patients with a survival rate between 93 and 100% [ 25 ]. Our patient is now 4 years post-placement of his first implant procedure and has been functioning without any issues.…”

Implant-Prosthetic Restoration of a Patient with Osteogenesis Imperfecta: A Case Report

“…To date, only a few case reports have been published on implant-prosthetic restorations in patients with OI [ 10 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ]. A Norwegian study reported a 95.7% survival rate of implants in patients with OI 25–135 months after prosthetic loading [ 22 ].…”

“…To date, only a few case reports have been published on implant-prosthetic restorations in patients with OI [ 10 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ]. A Norwegian study reported a 95.7% survival rate of implants in patients with OI 25–135 months after prosthetic loading [ 22 ]. Successful augmentative procedures using autologous retromolar bone, corticospongous grafts of the iliac crest and synthetic substitutes have also been reported [ 10 , 11 , 16 , 17 , 18 ].…”

Dental implants in individuals with osteogenesis imperfecta: a 6‐year follow‐up study

“…Although initially installed only in healthy individuals, dental implants have been increasingly placed in medically compromised persons since evidence on the effect of systemic diseases on dental implant success is limited. A few case reports have previously described successful implant treatment in persons with OI, whereas no study on the survival rate of dental implants in a group of individuals with OI had been published until our study in 2011.…”