Deproteinized bovine bone in association with guided tissue regeneration or enamel matrix derivatives procedures in aggressive periodontitis patients: a 1‐year retrospective study

Artzi, Zvi; Tal, Haim; Platner, Ori; Wasersprung, Nadav; Weinberg, Evgeny; Slutzkey, Gil; Gozali, Nir; Carmeli, Guy; Herzberg, Ran

doi:10.1111/jcpe.12413

Cited by 15 publications

(17 citation statements)

References 73 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In non‐randomized, comparative studies, the reported outcomes did not show a significant advantage of one surgical approach over another; the differences between groups were not significantly different. In both included RCT, no significant advantage of guided tissue regeneration procedures over EMD and simplified papilla preservation flap (SPPF) approaches could be found …”

Section: Resultsmentioning

confidence: 96%

Periodontal regeneration in aggressive periodontitis patients: A systematic review of the literature

Corbella

Weinstein

Francetti

et al. 2016

J of Invest & Clin Dent

View full text Add to dashboard Cite

The aim of the present study was to systematically review the existing literature on periodontal regenerative procedures in individuals affected by aggressive periodontitis (AgP). An electronic and manual search was performed using an ad hoc prepared search string. All types of study designs were considered acceptable for inclusion. Data about treated patients, baseline clinical parameters, type of surgery, and outcomes were extracted and recorded. A narrative evaluation of the results was performed. After the article-selection process, a total of 22 full-texts were included in the qualitative synthesis. Twelve papers were case reports; one was a retrospective study; six were non-randomized, comparative studies; and three papers were published on two randomized, controlled trials (RCT). Various biomaterials and surgical techniques were described in the included papers. Based on the existing literature, even considering the relatively low level of evidence, periodontal regenerative surgery could be successfully performed in patients affected by AgP. There is a substantial need of high-quality RCT to support this.

show abstract

Section: Resultsmentioning

confidence: 96%

Periodontal regeneration in aggressive periodontitis patients: A systematic review of the literature

Corbella

Weinstein

Francetti

et al. 2016

J of Invest & Clin Dent

View full text Add to dashboard Cite

show abstract

“…Allograft was added to the EMD to provide mechanical support for the soft tissue during the healing phase. 13 Stability of regenerative outcomes is expected after 1-year follow-up, as a similar study reported stability of CAL and PD and comparable results between 6 months and 1 year of regenerative treatment in patients with AgP. 8 Specifically, Rakmanee et al 8 reported 1.6-and 1.7-mm gain in CAL at 6 and 12 months, respectively, after GTR treatment in patients with AgP.…”

Section: Discussionmentioning

confidence: 89%

“…They reported similar clinical results in terms of PD reduction and CAL over 1 year of study. 13 Studies comparing GTR and EMD did not find significant differences in the clinical outcomes of two treatment modalities. 6,14 However, most studies did not take into account the different intrabony configurations as a variable factor in the interpretation of outcomes.…”

Section: Discussionmentioning

confidence: 96%

“…In a recent comparative study conducted by Artzi et al, 13 the authors retrospectively evaluated and compared the two regenerative periodontal procedures of GTR with deproteinized bone xenograft and bioabsorbable collagen membrane versus combination therapy of EMD plus deproteinized bone xenograft in young individuals with AgP. They reported similar clinical results in terms of PD reduction and CAL over 1 year of study 13 …”

Section: Discussionmentioning

confidence: 99%

“…Considering these reports, the non‐contained 1‐wall defect present at the left side was treated by GTR as opposed to EMD. Allograft was added to the EMD to provide mechanical support for the soft tissue during the healing phase 13 . Stability of regenerative outcomes is expected after 1‐year follow‐up, as a similar study reported stability of CAL and PD and comparable results between 6 months and 1 year of regenerative treatment in patients with AgP 8 .…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Treatment of Localized Aggressive Periodontitis With Guided Tissue Regeneration Technique and Enamel Matrix Derivative

Momen-Heravi

Kang

2017

Clin Adv Periodontics

View full text Add to dashboard Cite

Introduction: Aggressive periodontitis (AgP) is a form of periodontitis characterized by rapid attachment loss in otherwise healthy individuals. Although different treatment options have been explored for management of the disease, control of disease progression and subsequent regeneration of the attachment apparatus are considered the ideal treatment objectives. Limited evidence is available with respect to the efficacy of different regenerative materials in the treatment of AgP. Case Presentation: The present case report describes periodontal regeneration techniques and 6‐month outcomes in bilateral intrabony non‐contained defects around mandibular first molars in a 21‐year‐old patient diagnosed with localized AgP (LAgP). Periodontal lesions were treated with regenerative therapy with enamel matrix derivative (EMD) and allograft on the right side and allograft with bioabsorbable collagen membrane without EMD on the left side. Treatment yielded favorable clinical outcomes in terms of probing depth reduction, clinical attachment level gain, minimal gingival inflammation, and radiographic bone fill. Radiographic bone fill was observed after 6 months, suggesting possible periodontal regeneration. Conclusion: Both regeneration techniques used in this clinical report (guided tissue regeneration involving allograft and bioabsorbable membrane versus EMD combined with allograft without a barrier membrane) resulted in favorable outcomes in the treatment of deep (≥7 mm) non‐contained intrabony defects in LAgP.

show abstract

Biomaterials Selection – Cellular Interactions During Regenerative and Remodeling Phases

Binderman¹,

Halperin‐Sternfeld²,

Netanely³

et al. 2020

Bone Augmentation by Anatomical Region

View full text Add to dashboard Cite

Deproteinized bovine bone in association with guided tissue regeneration or enamel matrix derivatives procedures in aggressive periodontitis patients: a 1‐year retrospective study

Abstract: Surgical treatment of AgP patients by either GTR or by application of EMD/DBX yielded similarly successful clinical results at 1-year post-treatment.

Cited by 15 publications

References 73 publications

Periodontal regeneration in aggressive periodontitis patients: A systematic review of the literature

Periodontal regeneration in aggressive periodontitis patients: A systematic review of the literature

Treatment of Localized Aggressive Periodontitis With Guided Tissue Regeneration Technique and Enamel Matrix Derivative

Biomaterials Selection – Cellular Interactions During Regenerative and Remodeling Phases

Contact Info

Product

Resources

About