Derivation of a subtype-specific biochemical signature of endometrial carcinoma using synchrotron-based Fourier-transform infrared microspectroscopy

Multivariate Analysis for Fourier Transform Infrared Spectra of Complex Biological Systems and Processes

“…In this view, the advantage of LDA is that it makes it possible to reveal clusters, identifying objectively also the most contributory wavenumbers responsible for spectra discrimination [21,58]. In particular, the application of PCA-LDA to spectroscopic investigation of complex biological systems proved to be a useful tool for the identification of spectral biomarkers of the process under investigation [7,35,69,70,71].…”

“…One outstanding work, worth to mention here, was done by Kelly and colleagues [70], where the authors showed how infrared spectroscopy and multivariate techniques can be used as a novel diagnostic approach for endometrial cancer screening. They first demonstrated how SR-FTIR microspectroscopy with subsequent PCA-LDA allows the clear segregation of different subtypes of endometrial carcinoma.…”

Discrimination and Classification of Ginsenosides and Ginsengs Using Bis‐Boronic Acid Receptors in Dynamic Multicomponent Indicator Displacement Sensor Arrays

“…The basis of separation along F2 axis is based on the size of saccharides on the D ring, with disaccharides (Rb1, Rb3) higher than monosaccharides (Rd, Re, Rg1). The loading plots [40] (Figure 4 B) show a widely differential set of sensing ensembles, as they are found in all the quadrants of the plot. Such plots give the contribution of the host/indicator pairings to the F-axes.…”

A study of structural differences between liver cancer cells and normal liver cells using FTIR spectroscopy

“…investigate colorectal cancer [7,8], gastric cancer [9], prostate cancer [10], papillary thyroid carcinoma [11], breast cancer [12], ovarian cancer [13,14], urinary bladder cancer [15] and other cancers [16][17][18][19][20][21][22]. There were also some reports on FTIR spectroscopic study of liver diseases such as liver cancer [5,23,24] and hepatic fibrosis [25,26] [26].…”