Design and fabrication of cascade novel Fenton catalytic nanocomposite as theranostic agent for chemodynamic/photothermal synergistic tumor therapy

One-dimensional nanomaterials for cancer therapy and diagnosis

“…Huang's group created a novel CDT agent by combining MNO 2 FeOOH, PDA, and GQD (FePGMns) in 2022. 68 Due to the EPR effect, the material is deposited at the tumor site where FePGMns gradually decompose into metal ions (e.g., Mn 4+ /Mn 2+ and Fe 3+ /Fe 2+ ), PDA, and GQD under TME conditions. At that time, Mn 4+ /Mn 2+ and Fe 3+ /Fe 2+ were sequentially generated, and the cascaded Fenton catalyst reaction could be achieved.…”

Synthesis of manganese-oxide and palladium nanoparticles co-decorated polypyrrole/graphene oxide (MnO2@Pd@PPy/GO) nanocomposites for anti-cancer treatment

“…Thus, photothermal therapy (PTT) was achieved, furthermore, PTT will promote CDT according early reports, which will enhance the efficiency of anticancer. 34,61…”

Functionalized nanozyme with drug loading for enhanced tumour combination treatment of catalytic therapy and chemotherapy

“…[31][32][33][34] Polydopamine (PDA) was proved to be suitable to respond the high GSH concentration based tumour environment. 35 The oxidation reaction occurs during the polymerization of dopamine, and reduced GSH can inhibit the oxidation process and trigger the degradation of polydopamine. 36 Variable valence metal ions with high oxidation states can also react with glutathione.…”