2021
DOI: 10.4108/eai.8-1-2021.167845
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Design of a Novel Ensemble Model of Classification Technique for Gene-Expression Data of Lung Cancer with Modified Genetic Algorithm

Abstract: INTRODUCTION: Gene expression levels are important for identifying and diagnosing diseases like cancer. Gene expression microarray information contains a high extent feature set, which minimizes the performance and the accuracy of classifiers. OBJECTIVES: This paper proposes a Modified Genetic Algorithm (MGA) that is based on Classifier Subset Evaluators -Genetic Search (Eval-CSE_GS) for selecting the relevant feature subsets. The MGA feature selection procedure is applied to microarray information for cancer … Show more

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Cited by 5 publications
(4 citation statements)
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“…The accuracy of the classification is measured by the percentage of instances that are classified correctly, per Equation (7) Accuracy = (TP + TN)/(TP + TN+ FP + FN) (7) In order to calculate precision, divide the true-positive results with the sum of true positives and false positives, per Equation (8). Precision = TP/(TP + FP) (8) Similarly, Equation ( 9) is used to calculate the recall by dividing the true positives with true positives and false negatives.…”
Section: Evaluation Metricsmentioning
confidence: 99%
See 1 more Smart Citation
“…The accuracy of the classification is measured by the percentage of instances that are classified correctly, per Equation (7) Accuracy = (TP + TN)/(TP + TN+ FP + FN) (7) In order to calculate precision, divide the true-positive results with the sum of true positives and false positives, per Equation (8). Precision = TP/(TP + FP) (8) Similarly, Equation ( 9) is used to calculate the recall by dividing the true positives with true positives and false negatives.…”
Section: Evaluation Metricsmentioning
confidence: 99%
“…Over 10% of HCC cases recur after five years [6]. Most deaths from cancer caused by HCC occur in the United States [7]. Early identification [8] is an effective strategy to avoid cancer, but it is difficult to detect due to the number of causes that cause cancer.…”
Section: Introductionmentioning
confidence: 99%
“…Predictive models are based on a variety of factors, such as the characteristics of the initial cancer, the patient's age, the stage of the cancer and the type of treatment received. Tools such as the Online Recurrence Score (Oncotype DX) [10], Metastatic DNA Prognosis Score (MammaPrint) [11], and Molecular Profiling Signature Score (EndoPredict) are available to help clinicians assess the risk of recurrence in patients with breast cancer [12]. These predictive models can help clinicians decide whether a patient requires adjuvant chemotherapy, radiation therapy, or hormone therapy, or whether she should simply be monitored closely.…”
Section: Introductionmentioning
confidence: 99%
“…Many search methods calculate the importance of individual features and rank them accordingly and provide the best features from a given set[26]. This algorithm can simplify the data realization, decrease over fitting problem and the size of data storage.it also reduces over fitting, improves Accuracy, and reduces training time.…”
mentioning
confidence: 99%