The XRISM X-ray observatory will fly two advanced instruments, the Resolve high-resolution spectrometer and the Xtend wide-field imager. These instruments, particularly Resolve, pose calibration challenges due to the unprecedented combination of spectral resolution, spectral coverage, and effective area, combined with a need to characterize the imaging fidelity of the full instrument system to realize the mission's ambitious science goals. We present the status of the XRISM in-flight calibration plan, building on lessons from Hitomi and other X-ray missions. We present a discussion of targets and observing strategies to address the needed calibration measurements, with a focus on developing methodologies to plan a thorough and flexible calibration campaign and provide insight on calibration systematic error. We also discuss observations that exploit Resolve's spectral