Detection of Coccidian Parasites and their Clinical Manifestation, Treatment and Prophylaxis in HIV Infected Patients in Tribhuvan University Teaching Hospital

Basnet, A; Sherchan, BB; Rijal, Basista Prasad; Sharma, Swati; Khadga, Prem

doi:10.3126/sw.v8i8.3849

Cited by 9 publications

(6 citation statements)

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“…This may be due to the fact that opportunistic parasites are known to resolve spontaneously with immune restoration among HIV/AIDS patients on ART [9,10]. The association of these parasite for lower 200 cells/mm 3 CD4 count was in line with that of Varasani (97.8%), India (83%), in selected ART centers of Adama, Afar and Dire-Dawa (62.5%), in different part of Ethiopia (76.9%) and Hawassa (72%) [16,17,21,23,24]. …”

Section: Discussionmentioning

confidence: 63%

Prevalence of intestinal parasites and associated risk factors among HIV/AIDS patients with pre-ART and on-ART attending dessie hospital ART clinic, Northeast Ethiopia

et al. 2013

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BackgroundIntestinal parasites are a major concern in most developing countries where HIV/AIDS case are concentrate and almost 80% of AIDS patients die of AIDS-related infections. In the absence of ART, HIV/AIDS patients in developing countries unfortunately continue to suffer from the consequences of opportunistic parasites. But this prevalence has dramatically decreased in countries where antiretroviral agents are widely available. Therefore, the aim of this study was to assess the prevalence of intestinal parasite and risk factor among pre- ART and on ART adult HIV/ AIDS patients attending ART clinic in Dessie hospital.MethodsA comparative cross-sectional study was conducted among pre-ART and on ART adult HIV/AIDS patients of Dessie Hospital. A total of 272 (136 from each group) study subjects were selected by using systematic random sampling. Stool sample was collected and processed using direct wet mount, formol-ether concentration technique and modified Ziehl-Neelson staining techniques. A structured questionnaire was used to collect data on Sociodemographic & associated risk factors. Data was entered and analyzed by using SPSS 16 software and logistic regressions were applied to assess any association between explanatory factors and outcome variables.ResultsThe overall prevalence of IP in pre-ART and on-ART was 39% and 17.6%, respectively with significant decrease of intestinal parasite in the ART era (p < 0.001). All Cryptosporidium spps infections were found in the pre-ART patients and significantly associated for lower CD4 <200cells/mm3. Absence of toilet (AOR = 7.57; 95% CI = 1.3,44.22), source of water (AOR = 6.03; 95% CI = 1.14,31.98), living condition (AOR = 13.29, 95% CI = 5.14, 34.35); WHO stage (AOR = 6.06; 95% CI = 2.49,14.74) and ART status (AOR = 7.55; 95% CI = 3.24,17.59) have significant association with prevalence of intestinal parasite.ConclusionThe overall prevalence of IP was differ by ART status and opportunistic parasite like cryptosporidium spps were found in low CD4 counts in ART naive patients. This study identified some environmental and some clinical finding as determinant factor for IP infections. Therefore, public health measures and adherence to ART should be strengthened to improve the quality of life of these patients.

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Section: Discussionmentioning

confidence: 63%

Prevalence of intestinal parasites and associated risk factors among HIV/AIDS patients with pre-ART and on-ART attending dessie hospital ART clinic, Northeast Ethiopia

et al. 2013

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“…Moreover, study report on opportunistic parasitic infection among HIV seropositive patients and load of CD4 count in Nepal are very scarce and there is no representative baseline information in the country. 32 Hence, it is important to investigate further to determine the rate of infection with enteric opportunistic parasites to determine the rate of infection with enteric opportunistic parasite in HIV-AIDS patients in other regions of Nepal which will provide the level of endemicity of the country. Skilled manpower and laboratory support required to investigate the carrier, latent and clinical infection.…”

Section: Discussionmentioning

confidence: 99%

Enteric Opportunistic Parasitic Infections Among HIVSeropositive Patients in Kathmandu, Nepal

Sherchan

Ohara

Sakurada

et al. 2013

Kathmandu Univ. Med. J.

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Background Enteric opportunistic parasitic infections are the major source of diarrheal disease in developing countries mainly in Human Immunodeficiency virus (HIV) infected patients. Objective The study was to detect enteric parasites causing diarrhea and their association with immune status in HIV-seropositive patients. Methods The present study was conducted in Dirgh-Jeevan Health Care Research Center and Tribhuvan University Teaching Hospital, Public Health Research Laboratory, Kathmandu, Nepal between June 2010 and May 2011 involving 146 Human Immunodeficiency virus (HIV) positive patients. Serostatus from these patients were detected by Enzyme Linked Immunosorbent assay. CD4+ T cell counts were done by flow cytometry. Stool was examined for enteric parasites by microscopy with special staining methods. Results A total of 146 HIV sero-positive patients with and without diarrhea age between 20 to 45 years were included in the study. Of the 146 patients, the protozoan parasitic infection was found in 30.13% (44/146). Out of 146 patients, 78 had diarrhea in which parasitic infection was 39 (50%) and 7.35% (5/68) protozoal parasites positive cases did not have diarrhea. A significant difference (p<0.05) was observed in the level of infection of intestinal protozoan between the HIV seropositive with diarrhea and HIV-seropositive without diarrhea. Out of 43 patients whose CD4+ T cells were <200/?l, 29 (67.4%) had opportunistic parasitic infection whereas out of 103 patients whose CD4+ T cells were ?200/?l, only 15 (14.56%) had opportunistic parasitic infection (P < 0.05). Conclusion Enteric opportunistic parasitic infections were detected in 30.1% among HIV-seropositive patients and low CD4+ T count indicated high enteric opportunistic infection. Early detection of enteric parasitic infections will help in the management and to improve the quality of life for HIV-infected individuals. Kathmandu University Medical Journal | Vol.10 | No. 2 | Issue 38 | Apr – June 2012 | Page 14-17 DOI: http://dx.doi.org/10.3126/kumj.v10i2.7336

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“…In this study the prevalence of intestinal parasites among HIV/AIDS clients was 24.2% with 95%CI (18.9, 28.4). It is somewhat with studies done in China (23.2% protozoa, 4.3% helminthes)(10), Brazil (27%) (11) and Cameron (27.8%) (5).But it is less than that of studies done in Addis Ababa Zewditu hospital (34.3%)(6), and Jimma (39.56%)(7). More or less, it is higher than study done in Nepal (12.3%) (12).…”

Section: Resultsmentioning

confidence: 79%

“…Intestinal parasitic infection has been a major source of morbidity in tropical countries especially among HIV patients (3,4). Almost 80% of AIDS patients die from AIDS-related infections including intestinal parasites rather than HIV infection itself (5).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Intestinal Parasites and Associated Factors among HIV Patients who had Follow up at Debre Markos Referral Hospital,Northwest Ethiopia,from 2015-2019.

Gietaneh

Agegne

Gedif

2019

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Objective To assess prevalence of intestinal parasite and associated factors among patients with human immune deficiency virus (HIV)/ acquired immune deficiency syndrome (AIDS) in Debre markos referral hospital, Amhara region, Ethiopia from 2015-2019RESULTS This study revealed that, out of 380 patients, the prevalence of intestinal parasites was found to be 24.2% with95%CI (18.9, 28.4). The most predominant parasite was both forms of Entamoeba histolytica 11.3% followed by G.lambilia 8.9%, Strongyloides sterocoralis 2.4%, but A.lumbricoid 0.8% and H.worm 0.8% were the least detected. ART status had significant association with prevalence of intestinal parasites (AOR =3.566, CI: 1.882, 6.758).

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Detection of Coccidian Parasites and their Clinical Manifestation, Treatment and Prophylaxis in HIV Infected Patients in Tribhuvan University Teaching Hospital

Cited by 9 publications

References 10 publications

Prevalence of intestinal parasites and associated risk factors among HIV/AIDS patients with pre-ART and on-ART attending dessie hospital ART clinic, Northeast Ethiopia

Prevalence of intestinal parasites and associated risk factors among HIV/AIDS patients with pre-ART and on-ART attending dessie hospital ART clinic, Northeast Ethiopia

Enteric Opportunistic Parasitic Infections Among HIVSeropositive Patients in Kathmandu, Nepal

Prevalence of Intestinal Parasites and Associated Factors among HIV Patients who had Follow up at Debre Markos Referral Hospital,Northwest Ethiopia,from 2015-2019.

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