Detection of H₂O₂ at the Nanomolar Level by Electrode Modified with Ultrathin AuCu Nanowires

Abstract

Bimetallic AuCu nanowires (AuCuNWs) are synthesized via a facile water solution method at room temperature. Enhanced electrocatalytic activity is observed toward the oxidation of H2O2, which makes the AuCu nanowire, along with its unique catalytic properties, intriguing bifunctional mechanism, and surface atomic construction, a promising platform for the amplification of interfacing signal. A highly sensitive H2O2 biosensor is thus developed on the base of the as-prepared AuCuNW catalyst. A very low real determination limit (2.0 nM) was reached, and a linear range as wide as 5 orders of magnitude was demonstrated. In addition, a trace amount of H2O2, which was released from Raw 264.7 cells, was selectively detected, hinting at the possible applications for real-time quantitative detection of H2O2 in a biological environment.

Preparation of non‐covalent Metalloporphyrin/C60 Composite and its Electrocatalysis to Hydrogen Peroxide

“…In contrast, upon the following addition of 1.0 mM glucose, ascorbic acid (AA) and L‐cysteine, the currents at the three electrodes had trivial changes; while upon the second addition of 1.0 mM H 2 O 2 , the reduction currents experienced an increase. It comes to conclusion that glucose, ascorbic acid (AA) and L‐cysteine did hardly affect the current response of H 2 O 2 at TOAB/ZnTPPS 4 /C 60 /GCE, TOAB/FeTPPS 4 /C 60 /GCE and TOAB/CoTPPS 4 /C 60 /GCE, in agreement with the reported experimental results .…”

Electrochemical detection of carcinoembryonic antigen based on silver nanocluster/horseradish peroxidase nanocomposite as signal probe

“…On the other hand, the signal enhancement associated with the use of nanomaterial-biomolecue assemblies provides the basis for ultrasensitive detection of analyte targets [7][8][9]. Among the different kinds of nanomaterials, noble metal based nanomaterials, such metal nanoparticles, metal nanorod and metal nanowire have attracted significant research interest due to the unique optical and electrical properties [10,11]. For example, studies have proved metal nanomaterials could promote electron transfer and then enhance the catalytic activity of enzymes [12][13][14].…”

A Novel Electrochemical Aptamer Biosensor Based on DNAzyme Decorated Au@Ag Core-Shell Nanoparticles for Hg2+ Determination

“…Especially, bimetallic nanoparticles have shown better catalytic activity than the monometallic ones with the same elements. [26][27][28] For example, Wang et al 29 synthesized bimetallic AuCu nanowires (AuCuNWs) via a facile water solution method and the enhancing electrocatalytic activity toward the oxidation of H 2 O 2 was observed. DNAzymes with the character of biological enzymes are particularly appealing because they are easily synthesized and applied in catalytic signal amplification.…”