Determination of deltamethrin and its metabolite 3-phenoxybenzoic acid in male rat plasma by high-performance liquid chromatography

Facile and Sensitive Spectrophotometric Determination of Synthetic Pyrithroids in Their Formulations, Water and Grain Samples

“…The insecticides are highly stable under acidic conditions, though unstable at pH 8.0. Because of its significance, several methods have been developed for the determination of synthetic pyrethroids such as spectrophotometry Naidu, 1992, 1994), gas chromatography (Serodio and Noguira, 2005;Leng and Gries, 2005;Ramesh and Ravi, 2004;Sassine et al, 2004;Sannino et al, 2003) and high performance liquid chromatography (Leon Gonzalez et al, 2005;Parrilla Vazquez et al, 2005;Ding et al, 2004;Bicker et al, 2004;Loper and Anderson, 2003).…”

Rapid determination of the synthetic pyrethroid insecticide, deltamethrin, in rat plasma and tissues by HPLC

“…Other published HPLC methods [13][14][15][16][17] are laborious, in that they require day-long evaporation to dryness and have longer column retention times. With the current method, DLM was extracted from plasma by vortexing it in twice its volume of acetonitrile for 30 s. Acetonitrile in water (50%, v/v) was initially used to homogenize tissues to achieve better extraction.…”

“…Chemical assays have included gas chromatography [9,10], thin-layer chromatography [11,12], and high-performance liquid chromatography (HPLC) with ultraviolet detection. HPLC methods have been utilized to determine concentrations of the pyrethroid, deltamethrin (DLM) in milk, foods, environmental specimens, blood and various tissues [13][14][15][16][17]. Isolation and concentration of DLM in samples has involved a combination of liquid-liquid and solid phase extraction.…”

“…Serial blood sampling and sacrifices of groups of animals in PK time-course experiments produce a myriad of samples to be analyzed. To our knowledge, only Ding et al [17,30] reported a fully-validated HPLC analytical method for DLM. Its limit of quantitation was 0.1 g/ml plasma.…”

Optical sensing of 3-phenoxybenzoic acid as a pyrethroid pesticides exposure marker by surface imprinting polymer capped on manganese-doped zinc sulfide quantum dots

“…Several other methods have been reported in the analysis of pyrethroid metabolites. These include high-performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry (LC-MS) [29,30], gas chromatography (GC), gas chromatography-mass spectrometry (GC-MS) [31][32][33][34] and immunoassay based methods [35,36]. Although, these methods have an advantage to quantify 3-PBA in several matrices, but they are not compatible for on-field sensing and monitoring applications.…”