Determination of ethambutol MICs for Mycobacterium tuberculosis and Mycobacterium avium isolates by resazurin microtitre assay

Abstract

REMA can be used as a rapid and inexpensive method for mycobacterial drug susceptibility testing against ethambutol. In comparison with the agar method, the MICs determined by REMA can more accurately be correlated with achievable plasma concentrations of antimycobacterial agents.

Role of embCAB gene mutations in ethambutol resistance in Mycobacterium tuberculosis isolates from India

“…Drug susceptibility testing of MTB isolates to the antitubercular drugs RIF, INH, EMB and STR (Sigma Chemical Co., St Louis, MO) was done on LJ medium according to the standard proportion method [11]. An isolate showing ≥1% growth on drug-containing slopes in comparison with drug-free slopes was considered resistant, otherwise it was considered as sensitive.…”

Xanthates: Metabolism by Flavoprotein-Containing Monooxygenases and Antimycobacterial Activity

“…As a whole, some of the xanthate analogues tested in this study showed a moderate level of bacteriostatc antimycobacterial activity, in most cases comparable or even higher than that of the reference drug ethambutol (Jadaun et al, 2007).…”

Chemical composition and in vitro antibacterial activities of traditional medicinal plant: Olea sp

“…was determined for the tested Gram-negative bacteria ( The minimal inhibitory concentrations (MICs) were determined using Micro-dilution method. This method used by many authors to determine the MIC for many plant extracts [32]. The selected plant extracts were found to be effective on the standard and clinical bacterial isolates.…”