Determination of haemodynamic significance of intermediate coronary lesions using three-dimensional coronary reconstruction

Saad, Mohammed; Khattab, Ahmed A.; Kassner, Guido; Abdel‐Wahab, Mohamed; Richardt, Gert

doi:10.4244/eijv5i5a93

Cited by 14 publications

(9 citation statements)

References 29 publications

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“…Three-dimensional angiography has been recently validated [20] and could overcome the main limitations of 2-D angiography such as vessel foreshortening, poor representation of the eccentric lesions according to the projection view, providing more detailed geometric information about coronary artery lesions [21,22].…”

Section: Discussionmentioning

confidence: 99%

Bifurcation lesions: Functional assessment by fractional flow reserve vs. anatomical assessment using conventional and dedicated bifurcation quantitative coronary angiogram

Sarno¹,

Garg²,

Onuma³

et al. 2010

Cathet Cardio Intervent

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Section: Discussionmentioning

confidence: 99%

Bifurcation lesions: Functional assessment by fractional flow reserve vs. anatomical assessment using conventional and dedicated bifurcation quantitative coronary angiogram

Sarno¹,

Garg²,

Onuma³

et al. 2010

Cathet Cardio Intervent

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“…They found significant correlation between FFR and cross-sectional area percentage stenosis (AS) in 3D. Compared with FFR, the 3D AS of 57% had the highest sensitivity and specificity for determining the significance of the lesion [14].…”

Section: Discussionmentioning

confidence: 93%

“…Few studies have compared 3D-QCA and FFR in intermediate coronary stenoses [14,15]. Saad et al reported better accuracy of 3D-QCA than 2D-QCA in predicting FFR b 0.75.…”

Section: Discussionmentioning

confidence: 98%

Plaque volume derived from three-dimensional reconstruction of coronary angiography predicts the fractional flow reserve

Kolozsvári

Tar

Lugosi

et al. 2012

International Journal of Cardiology

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“…This new imaging technique is a computer based algorithm that uses two 2D images to create a three dimensional rendering. It takes a short time to reconstruct images per patient and can be done immediately or at a later period of time with little additional cost ( 22 , 23 ).…”

Section: Discussionmentioning

confidence: 99%

Three Dimensional Quantitative Coronary Angiography Can Detect Reliably Ischemic Coronary Lesions Based on Fractional Flow Reserve

et al. 2015

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Conventional coronary angiography (CAG) has limitations in evaluating lesions producing ischemia. Three dimensional quantitative coronary angiography (3D-QCA) shows reconstructed images of CAG using computer based algorithm, the Cardio-op B system (Paieon Medical, Rosh Ha'ayin, Israel). The aim of this study was to evaluate whether 3D-QCA can reliably predict ischemia assessed by myocardial fractional flow reserve (FFR) < 0.80. 3D-QCA images were reconstructed from CAG which also were evaluated with FFR to assess ischemia. Minimal luminal diameter (MLD), percent diameter stenosis (%DS), minimal luminal area (MLA), and percent area stenosis (%AS) were obtained. The results of 3D-QCA and FFR were compared. A total of 266 patients was enrolled for the present study. FFR for all lesions ranged from 0.57 to 1.00 (0.85 ± 0.09). Measurement of MLD, %DS, MLA, and %AS all were significantly correlated with FFR (r = 0.569, 0609, 0.569, 0.670, respectively, all P < 0.001). In lesions with MLA < 4.0 mm2, %AS of more than 65.5% had a 80% sensitivity and a 83% specificity to predict FFR < 0.80 (area under curve, AUC was 0.878). 3D-QCA can reliably predict coronary lesions producing ischemia and may be used to guide therapeutic approach for coronary artery disease.Graphical Abstract

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Determination of haemodynamic significance of intermediate coronary lesions using three-dimensional coronary reconstruction

Cited by 14 publications

References 29 publications

Bifurcation lesions: Functional assessment by fractional flow reserve vs. anatomical assessment using conventional and dedicated bifurcation quantitative coronary angiogram

Bifurcation lesions: Functional assessment by fractional flow reserve vs. anatomical assessment using conventional and dedicated bifurcation quantitative coronary angiogram

Plaque volume derived from three-dimensional reconstruction of coronary angiography predicts the fractional flow reserve

Three Dimensional Quantitative Coronary Angiography Can Detect Reliably Ischemic Coronary Lesions Based on Fractional Flow Reserve

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