Determination of melamine in air by high-performance liquid chromatography with ultraviolet detection

Pukkila, Jari; Peltonen, Kimmo; Savolainen, Tuure

doi:10.1016/s0021-9673(00)93992-x

Cited by 18 publications

(17 citation statements)

References 7 publications

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“…Two prior studies only measured ambient melamine exposure either from one laboratory chamber or from the field with different exposure sources. 18,19 Pukkila et al first measured ambient melamine concentration in the process of epoxy powder coating curing in the laboratory and the highest melamine concentration was found in 400 mg/m 3 . 18 Recently, Yassine et al measured ambient melamine emission from a diesel engine employing selective catalytic reduction technology and found the exposure level to be nondetectable to 11.0 mg/L.…”

Section: Discussionmentioning

confidence: 99%

“…18,19 Pukkila et al first measured ambient melamine concentration in the process of epoxy powder coating curing in the laboratory and the highest melamine concentration was found in 400 mg/m 3 . 18 Recently, Yassine et al measured ambient melamine emission from a diesel engine employing selective catalytic reduction technology and found the exposure level to be nondetectable to 11.0 mg/L. 19 A wide range of urinary melamine concentrations from nondetection up to approximately 2000 mg/mmol was found in infants or children who were exposed to melamine-tainted milk in China, Taiwan, and Hong Kong (Supplemental Table 10).…”

Section: Discussionmentioning

confidence: 99%

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Ambient Melamine Exposure and Urinary Biomarkers of Early Renal Injury

Peng

Liu

et al. 2015

Journal of the American Society of Nephrology

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Information about environmental exposure to melamine and renal injury in adults is lacking. We investigated this relationship in 44 workers at two melamine tableware manufacturing factories in Taiwan (16 manufacturers, eight grinders, ten packers, and ten administrators) and 105 nonexposed workers (controls) at one shipbuilding company who were enrolled in August-December of 2012. For melamine workers, personal and area air samples were obtained at the worksite over 1 workweek (Monday-Friday). In the same week, pre-and post-shift one-spot urine samples were collected each workday and one first-spot urine sample was collected on each weekend morning and the following Monday morning. For each control, a one-spot urine sample was collected on Friday morning. A blood sample was also obtained from each participant at this time. Melamine levels were measured in air, urine, and serum, and early renal injury biomarkers were measured in urine. Urinary melamine concentrations in manufacturers increased sharply between pre-and post-shift measurements on Monday, remained significantly elevated throughout the workweek, and decreased over the weekend; changes in urinary melamine concentrations were substantially lower for other melamine workers. Manufacturers were exposed to the highest concentrations of ambient melamine and had significantly higher urinary and serum melamine concentrations than did the controls (P,0.001). Urinary melamine levels were positively associated with urinary N-acetyl b-D-glucosaminidase (NAG) levels but not microalbumin levels, and the detectable b2-microglobulin rate increased in the manufacturers group. In conclusion, ambient melamine exposure may increase the levels of urinary biomarkers of renal tubular injury in this occupational setting.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Ambient Melamine Exposure and Urinary Biomarkers of Early Renal Injury

Peng

Liu

et al. 2015

Journal of the American Society of Nephrology

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“…The UV absorption of melamine is reported in wide range between 210 and 240 nm, such as 214 nm (Yokley et al, 2000), 215 nm (Pukkila et al, 1987), 220 nm (Muñiz-Valencia et al, 2008), 236 nm (He et al, 2008), 240 nm (China, 2008, etc. The difference of detection wavelength maybe related to the polarity and cut-off wavelengths of the solvents used in the mobile phases.…”

Section: Uv Detection Wavelength Of Melaminementioning

confidence: 99%

“…However, a time-consuming derivatization procedure is usually essential for GC separation of melamine (Lin, 2009;Stoks & Schwartz, 1979;Sun et al, 2010;Tittlemier, 2010;Toth & Bardalaye, 1987). Therefore, HPLC and related techniques (sometimes coupled with MS detection) are the most commonly chosen to determine melamine in various kind of samples (China, 2008;He, Liu, Huang, Yang, & Liao, 2008;Lin, 2009;Pukkila, Peltonen, & Savolainen, 1987;Sun et al, 2010;Tittlemier, 2010;Yokley, Mayer, Rezaaiyan, Manuli, & Cheung, 2000). Most of those HPLC methods involved in reversed-phase liquid chromatography (RP-HPLC) (Lin, 2009;Sun et al, 2010;Tittlemier, 2010), and sometimes ion-exchange chromatography (HPIC) (China, 2008).…”

Section: Introductionmentioning

confidence: 99%

Determination of melamine in dairy products by HILIC-UV with NH2 column

Zheng

et al. 2012

Food Control

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“…Melamine has been generally analyzed in different matrices by liquid chromatography with ultraviolet detection or diode array detection (DAD) [12][13][14][15][16][17], liquid chromatography/tandem mass spectrometry [18][19][20][21][22], gas chromatography [23], enzymelinked immunosorbent assay [22,24], capillary electrophoresis [25], surface desorption atmospheric pressure chemical ionization mass spectrometry [26], capillary zone electrophoresis with quadrupole/time of flight mass spectrometry (CZE-Q/TOF) [27], CZE-DAD [28] and infrared spectroscopy [29]. A maximum of 1 mg/kg of infant formula was the limit in China [30] but any level of contamination level for melamine was still not established by FDA of America in infant formula.…”

Section: Introductionmentioning

confidence: 99%