Determination of Tablet Strength by the Diametral-Compression Test

Evaluation of the Role of Pores during Strength Testing in Compacts Made from Different Particle Size Fractions of Sucrose

“…Irwin 25) described the relationship between specimen tensile strength (s t ), critical stress intensity factor (K IC ) and crack length (a) as follows: (4) This equation can be used in two ways to study the relationship between the fracture mechanics approach and the strength of the cylindrical disk specimens. First, the equation can be solved for the crack length using extrapolated data for the critical stress intensity factor at the various porosity values.…”

Solid-State Characterization and Dissolution Properties of Meloxicam–Moringa Coagulant–PVP Ternary Solid Dispersions

“…Angle of repose, Carr's compressibility index, and Hausner's ratio of the optimized batch was found to be 26.77°, 14.622, and 1.1712, respectively, indicating good flowability (28). The values of a and b in the Kawakita plot of SDMMP were 0.5789 and 0.05906, respectively, indicating large reduction in volume of powder bed with increase in number of tapings and hence good compressibility (26).…”

“…where D is diameter, t is thickness of compacts, and F is the force required to break the compacts (28). Pressure-tensile strength data were subject to Leuenberger equation to calculate compression susceptibility (γ) and compactibility (σ tmax ) of agglomerates.…”

Compaction, compression and drug release properties of diclofenac sodium and ibuprofen pellets comprising xanthan gum as a sustained release agent

“…Rep. of Germany) at a compression rate of 5 mm/min. The tensile strength of the tablets (σ) was calculated according to Fell and Newton (1970) (Eq. (4)) by applying the force needed to fracture the tablet (P) and the diameter (D) and thickness (T) of the tablet.…”