Proceedings. Eighth Annual IEEE International Conference and Workshop on the Engineering of Computer Based Systems-Ecbs 2001
DOI: 10.1109/ecbs.2001.922416
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Developing a traceable domain reference architecture to support clinical trials at the National Cancer Institute. An experience report

Abstract: This paper presents the requirements gathering and software architecture derivation approach developed by the Universio of Texas at Austin and leveraged by the National Cancer Institute (NCl) in their efsorts to automate the creation, nlanagement, and evaluation of clinical trials. NCI must face the complexity of managing clinical trials and coordinating large numbers and varied types of stakeholders. The Systems Engineering Process Activities (SEPA) from the University of Texas at Austin is well suited to add… Show more

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Cited by 5 publications
(6 citation statements)
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“…With regard to RQ1, Figure 2 summarizes the 162 reference architectures found by year 11 , highlighting the amount of them that were designed in the academic context (in gray color), industry context (in dark-blue color), and collaboration between industry-academy context (in light-blue color). Table 5 in Appendix A, lists the final set of studies reporting reference architectures and that were analyzed in this SMS.…”
Section: Existing Reference Architecturesmentioning
confidence: 99%
“…With regard to RQ1, Figure 2 summarizes the 162 reference architectures found by year 11 , highlighting the amount of them that were designed in the academic context (in gray color), industry context (in dark-blue color), and collaboration between industry-academy context (in light-blue color). Table 5 in Appendix A, lists the final set of studies reporting reference architectures and that were analyzed in this SMS.…”
Section: Existing Reference Architecturesmentioning
confidence: 99%
“…Simulation is a powerful technique for evaluating performance properties of software architectures [10][11][12], however application of simulation techniques requires specialized knowledge to (1) translate an architecture specification into suitable input to a simulation tool, and (2) interpret the results of simulation and relate those results back to the architecture specification in a meaningful way. This process is iterative: as performance issues are detected, the architecture specification must be corrected, and simulation must be re-applied to verify the corrections (Figure 1).…”
Section: Arcade Approachmentioning
confidence: 99%
“…Arcade can be used for performance evaluations of the implementation-specific SEPA architecture levels as well, but such analyses are not the focus of this paper. The SEPA methodology, tools, and associated artifacts have been employed in association with several large multi-year projects, including development of DRAs for clinical trial management for the National Cancer Institute [1], and for the Enhanced Consequence Management, Planning and Support System (ENCOMPASS), a DARPA system designed to support information dissemination and coordination among first responders (e.g., fire, police, EMS) during incident response [4].…”
Section: Introductionmentioning
confidence: 99%
“…Barber et al [6] would seem to have the strongest claim in this regard. However, there does not appear to be many field trials, if any, beyond [6].…”
Section: Accessibility To the Professional And Expressive Powermentioning
confidence: 95%
“…Barber [5,6] both support domain restriction, and their refinement method is strongly based on the domain architecture.…”
Section: Domain and Technology Restrictionmentioning
confidence: 99%