Development and characterization of silver and zinc doped bioceramic layer on metallic implant materials for orthopedic application

Furkó, Mónika; Jiang, Yunhong; Wilkins, Terry; Balázsi, Csaba

doi:10.1016/j.ceramint.2015.12.006

Cited by 22 publications

(14 citation statements)

References 18 publications

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“…Micro-arc oxidation (MAO) also known as plasma electrolytic oxidation (PEO), is a novel method to prepare an in situ CaP coating with a wide range of physical and chemical properties on surface of valve metals and their alloys. MAO is considered to be a promising electrochemical method, allowing a synthesis of porous, rough, hydrophilic, and firmly adherent CaP coatings on metal surfaces and incorporation of other essential trace elements into the coatings [ 17 , 18 , 19 , 20 ]. The reviews [ 21 , 22 , 23 , 24 ] noted that the rough and porous CaP biocoatings can facilitate efficient osseointegration and biomechanical fixation due to the excellent bone cell adhesion and growth inside the microtopography on the coating surface.…”

Section: Introductionmentioning

confidence: 99%

Zn- or Cu-containing CaP-Based Coatings Formed by Micro-Arc Oxidation on Titanium and Ti-40Nb Alloy: Part II—Wettability and Biological Performance

et al. 2020

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This work describes the wettability and biological performance of Zn- and Cu-containing CaP-based coatings prepared by micro-arc oxidation on pure titanium (Ti) and novel Ti-40Nb alloy. Good hydrophilic properties of all the coatings were demonstrated by the low contact angles with liquids, not exceeding 45°. An increase in the applied voltage led to an increase of the coating roughness and porosity, thereby reducing the contact angles to 6° with water and to 17° with glycerol. The free surface energy of 75 ± 3 mJ/m2 for all the coatings were determined. Polar component was calculated as the main component of surface energy, caused by the presence of strong polar PO43− and OH− bonds. In vitro studies showed that low Cu and Zn amounts (~0.4 at.%) in the coatings promoted high motility of human adipose-derived multipotent mesenchymal stromal cells (hAMMSC) on the implant/cell interface and subsequent cell ability to differentiate into osteoblasts. In vivo study demonstrated 100% ectopic bone formation only on the surface of the CaP coating on Ti. The Zn- and Cu-containing CaP coatings on both substrates and the CaP coating on the Ti-40Nb alloy slightly decreased the incidence of ectopic osteogenesis down to 67%. The MAO coatings showed antibacterial efficacy against Staphylococcus aureus and can be arranged as follows: Zn-CaP/Ti > Cu-CaP/TiNb, Zn-CaP/TiNb > Cu-CaP/Ti.

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Section: Introductionmentioning

confidence: 99%

Zn- or Cu-containing CaP-Based Coatings Formed by Micro-Arc Oxidation on Titanium and Ti-40Nb Alloy: Part II—Wettability and Biological Performance

et al. 2020

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“…These days, one of the most distressing complications that could appear after surgery is considered the apparition of a post operatory infection [5,6]. In most cases, the infection appears because of the bacterial cells, which adhere either to an implantable medical device (when is the case), either on the tissue surrounding the surface of the implant, or simply on the surface of the wound [7,8]. These types of bacterial adhesions on implantable devices are some of the most frightening problems that can occur in the dentistry, orthopedic, and cardiovascular field, because they usually lead to severe life treating infections due to the development The morphology of the samples was investigated by scanning electron microscopy (SEM), using a HITACHI S4500 microscope (Hitachi, Ltd., Tokyo, Japan) equipped with an X-ray energy dispersive spectroscopy (EDX) system.…”

Section: Introductionmentioning

confidence: 99%

Zinc Doped Hydroxyapatite Thin Films Prepared by Sol–Gel Spin Coating Procedure

et al. 2019

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In this study, ZnHAp layers deposited on a Si substrate were obtained by a sol–gel spin-coating procedure. The ZnHAp solutions used to obtain the ZnHAp coatings were investigated by dynamic light scattering (DLS) analysis, ζ-potential, ultrasound measurements, and flame atomic absorption spectrometry (AAS). The average measured hydrodynamic diameter from the DLS analysis, ζ-potential, and ultrasound measurements were analyzed so as to characterize and estimate the stability of the ZnHAp nanoparticles. The AAS results confirmed the presence of zinc in the gels used in the preparation of the ZnHAp layers. The layers were investigated by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The XRD results revealed the diffraction peaks of the hexagonal hydroxyapatite in all of the investigated samples. The morphology of the ZnHAp coatings annealed at 500 °C (ZnHAp-500) and 700 °C (ZnHAp-700), which evidenced that no fissures or cracks formed on the surface of the coatings. The biocompatibility assays indicated that the ZnHAp coatings did not present any toxicity towards the HeLa cells. Furthermore, the study regarding the cytotoxicity of the ZnHAp layers against microorganisms emphasized that ZnHAp coatings exhibited an inhibitory effect towards S. aureus bacterial cells and also towards C. albicans fungal cells.

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“…The Tafel plots (Fig. 3) for the alloy deposits obtained in absence In the present study a low corrosion current infers that a strong thin barrier layer has been formed on the surface of alloy [14] that reduces the active corrosion sites and makes the deposit more corrosive resistance towards sulphate ions. Based on the obtained corrosion current results, corrosion rate was calculated.…”

Section: Tafel Polarizationmentioning

confidence: 47%

“…It was seen, a low I corr was obtained for the alloy deposits, obtained in the presence of 0.25 to 0.75g/L benzaldehyde in the bath. It was known that corrosion resistance of any alloy depends on the ability to form surface protective film.In the present study a low corrosion current infers that a strong thin barrier layer has been formed on the surface of alloy[14] that reduces the active corrosion sites and makes the deposit more corrosive…”

mentioning

confidence: 58%

Effect of Additives on Electrodeposition of Zinc-Nickel Alloy On Mild Steel

Chelike

Sundari

2019

Asian J. Chem.

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Considering the good corrosion resistance of Zn-Ni alloy, it is selected in the present study to be the protective coating on mild steel and it is considered as a strong candidate for the replacement of environmentally hazardous cadmium. Zn-Ni alloy coating is applied by electrodeposition at optimum temperature, current density and time. The bath solution used is consisting of EDTA as complexing agent. The electrodeposition is also carried out with tartaric acid and benzaldehyde additives to have good corrosion resistance and brightness. The electrodeposits obtained with and without additives are examined for nature and alloy composition. The corrosion behaviour of the electrodeposits is studied by Tafel polarization and electrochemical impedance spectroscopy.

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Development and characterization of silver and zinc doped bioceramic layer on metallic implant materials for orthopedic application

Cited by 22 publications

References 18 publications

Zn- or Cu-containing CaP-Based Coatings Formed by Micro-Arc Oxidation on Titanium and Ti-40Nb Alloy: Part II—Wettability and Biological Performance

Zn- or Cu-containing CaP-Based Coatings Formed by Micro-Arc Oxidation on Titanium and Ti-40Nb Alloy: Part II—Wettability and Biological Performance

Zinc Doped Hydroxyapatite Thin Films Prepared by Sol–Gel Spin Coating Procedure

Effect of Additives on Electrodeposition of Zinc-Nickel Alloy On Mild Steel

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