Development in Neurospora crassa

Blue Light Overrides Repression of Asexual Sporulation by Mating Type Genes in the BasidiomyceteCoprinus cinereus

“…Strikingly, sexual development in M. grisea and N. crassa is also positively regulated by light (Degli Innocenti and Russo, 1984;Silue and Nottegham, 1990) and common regulatory elements are used in light control of sexual and asexual development (Degli Innocenti and Russo, 1984;Ballario et al, 1996;Linden and Macino, 1997). About one-third of all genes affecting fruiting in N. crassa also affect conidiogenesis, indicating that there is much in common between the pathways of sexual and asexual differentiation (Russo and Pandit, 1992). The situation is similar in Coprinus, where about one-third of mutants defective in fruit body initiation are also defective in oidiation (U. Kü es et al, in preparation).…”

Differential stress gene expression during the development of Neurospora crassa and other fungi

“…A concomitant increase in reactive oxygen species may then induce higher activity of hsp genes comparable to the induction by H P O P [37]. In acon-2, a developmental mutant of N. crassa (review : [18]), the formation of conidia and thus the higher expression of hsc70 and grp78 is delayed for more than 24 h compared to the wildtype even though the aerial hyphae are equally exposed to air [30,33]. This is not compatible with the assumption that the induction of hsp genes depends on a certain time of exposure to oxygen.…”

“…A detailed developmental program has been described by Springer and Yanofsky [13] which involves sequential gene activation and inactivation. Further developmental steps of aerial hyphae, such as minor and major constriction budding and formation of connectives, can be blocked by mutational defects in speci¢c genes (review: [18]). …”