Development of a 3D ultrasound guidance system for permanent breast seed implantation

Michael, Justin; Morton, Daniel; Batchelar, Deidre; Hilts, Michelle; Crook, Juanita; Fenster, Aaron

doi:10.1002/mp.12990

Cited by 8 publications

(3 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, since we chose to use magnetic encoders in the tracking system that detect the magnetic field of the rotary shaft in the radial‐transverse cylindrical plane (for a reduced size advantage), any manufacturing error in the magnetic field alignment would increase the measured joint errors due to the nonlinear nature of the detected magnetic field. Although we believe the accuracy we achieved to be sufficient, calibration of each encoded joint could be completed during assembly of the system 38 to reduce this error as the off‐axis magnetic field is still extremely consistent and repeatable.…”

Section: Discussionmentioning

confidence: 99%

Geometrically variable three‐dimensional ultrasound for mechanically assisted image‐guided therapy of focal liver cancer tumors

et al. 2020

Self Cite

View full text Add to dashboard Cite

Purpose Image‐guided focal ablation procedures are first‐line therapy options in the treatment of liver cancer tumors that provide advantageous reductions in patient recovery times and complication rates relative to open surgery. However, extensive physician training is required and image guidance variabilities during freehand therapy applicator placement limit the sufficiency of ablation volumes and the overall potential of these procedures. We propose the use of three‐dimensional ultrasound (3D US) to provide guidance and localization of therapy applicators, augmenting current ablation therapies without the need for specialized procedure suites. We have developed a novel scanning mechanism for geometrically variable 3D US images, a mechanical tracking system, and a needle applicator insertion workflow using a custom needle applicator guide for targeted image‐guided procedures. Methods A three‐motor scanner was designed to use any commercially available US probe to generate accurate, consistent, and geometrically variable 3D US images. The designed scanner was mounted on a counterbalanced stabilizing and mechanical tracking system for determining the US probe orientation, which was assessed using optical tracking. Further exploiting the utility of the motorized scanner, an image‐guidance workflow was developed that moved the probe to any identified target within an acquired 3D US image. The complete 3D US guidance system was used to perform mock targeted interventional procedures on a phantom by selecting a target in a 3D US image, navigating to the target, and performing needle insertion using a custom 3D‐printed needle applicator guide. Registered postinsertion 3D US images and cone‐beam computed tomography (CBCT) images were used to evaluate tip targeting errors when using the motors, tracking system, or mixed navigation approaches. Two 3D US image geometries were investigated to assess the accuracy of a small‐footprint tilt approach and a large field‐of‐view hybrid approach for a total of 48 targeted needle insertions. 3D US image quality was evaluated in a healthy volunteer and compared to a commercially available matrix array US probe. Results A mean positioning error of 1.85 ± 1.33 mm was observed when performing compound joint manipulations with the mechanical tracking system. A combined approach for navigation that incorporated the motorized movement and the in‐plane tracking system corrections performed the best with a mean tip error of 3.77 ± 2.27 mm and 4.27 ± 2.47 mm based on 3D US and CBCT images, respectively. No significant differences were observed between hybrid and tilt image acquisition geometries with all mean registration errors ≤1.2 mm. 3D US volunteer images resulted in clear reconstruction of clinically relevant anatomy. Conclusions A mechanically tracked system with geometrically variable 3D US provides a utility that enables enhanced applicator guidance, placement verification, and improved clinical workflow during focal liver tumor ablation procedures. Evaluations of the tracking accu...

show abstract

Section: Discussionmentioning

confidence: 99%

Geometrically variable three‐dimensional ultrasound for mechanically assisted image‐guided therapy of focal liver cancer tumors

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…Figure 1a shows the design of the 3DUS system (32). Briefly, a 2D US probe (BK Medical 8811, Peabody, MA) is driven by a motor through a hybrid (linear and tilt) motion to generate 3DUS images.…”

Section: Dus System Designmentioning

confidence: 99%

“…A novel 3DUS system, with the ability to guide PBSI needle insertion, was developed specifically for PBSI in collaboration with Robarts Research Institute (London, ON) (32). In this study, we work toward implementing 3DUS into PBSI planning by characterizing the 3DUS system and developing a method to rigidly register 3DUS images to CT images used in planning.…”

Section: Introductionmentioning

confidence: 99%

Characterization and registration of 3D ultrasound for use in permanent breast seed implant brachytherapy treatment planning

et al. 2021

Self Cite

View full text Add to dashboard Cite

Permanent breast seed implant (PBSI) brachytherapy is a novel technique for earlystage breast cancer. Computed tomography (CT) images are used for treatment planning and freehand 2D ultrasound for implant guidance. The multimodality imaging approach leads to discrepancies in target identification. To address this, a prototype 3D ultrasound (3DUS) system was recently developed for PBSI. In this study, we characterize the 3DUS system performance, establish QA baselines, and develop and test a method to register 3DUS images to CT images for PBSI planning. METHODS AND MATERIALS: 3DUS system performance was characterized by testing distance and volume measurement accuracy, and needle template alignment accuracy. 3DUS-CT registration was achieved through point-based registration using a 3D-printed model designed and constructed to provide visible landmarks on both images and tested on an in-house made gel breast phantom. RESULTS: The 3DUS system mean distance measurement accuracy was within 1% in axial, lateral, and elevational directions. A volumetric error of 3% was observed. The mean needle template alignment error was 1.0 AE 0.3 and 1.3 AE 0.5 mm. The mean 3DUS-CT registration error was within 3 mm when imaging at the breast centre or across all breast quadrants. CONCLUSIONS: This study provided baseline data to characterize the performance of a prototype 3DUS system for PBSI planning and developed and tested a method to obtain accurate 3DUS-CT image registration for PBSI planning. Future work will focus on system validation and characterization in a clinical context as well as the assessment of impact on treatment plans.

show abstract

A postimplant dosimetry simulation framework for robustness evaluation in permanent breast seed implant brachytherapy

Zhang,

Andrews,

Batchelar

et al. 2024

Brachytherapy

View full text Add to dashboard Cite

Development of a 3D ultrasound guidance system for permanent breast seed implantation

Cited by 8 publications

References 35 publications

Geometrically variable three‐dimensional ultrasound for mechanically assisted image‐guided therapy of focal liver cancer tumors

Geometrically variable three‐dimensional ultrasound for mechanically assisted image‐guided therapy of focal liver cancer tumors

Characterization and registration of 3D ultrasound for use in permanent breast seed implant brachytherapy treatment planning

A postimplant dosimetry simulation framework for robustness evaluation in permanent breast seed implant brachytherapy

Contact Info

Product

Resources

About