Development of layer I of the human cerebral cortex after midgestation: Architectonic findings, immunocytochemical identification of neurons and glia, and in situ labeling of apoptotic cells

Cytoarchitectural and Axonal Maturation in Human Auditory Cortex

“…In hamster Padilla and Marin-Padilla 1982) that nonspecific stimulation of cortical plate neurons through their visual cortex, deep layer afferent and efferent axons form synchronously during the days preceding and apical dendrites plays a vital role in their structural and functional maturation. In support of this view, the following birth (Lent et al 1990;Miller et al 1993). Human thalamocortical axons, visualized by GAP-43 time when the maximum number of NF-expressing axons is present in the marginal layer is the late fetal labeling in visual cortex (Honig et al 1996) and by AChE in auditory cortex (Krmpotic-Nemancic 1983;Jouandet et al 1985;Auladell et al 1995 Pereira et al 1999) and the 3rd postnatal month in in the weeks before birth and attain mature myelin kittens (Feng and Brugge 1983).…”

“…In rat visual cortex, thalatical surface. As they traverse the layer, they contact and synapse with large numbers of apical dendritic mocortical connections are established on embryonic days 17-19, at which time axons from layers 5 and 6 tufts of deeper-lying pyramidal cells (Baloyannis 1993;Spreafico et al 1999). It has been suggested (Marinextend toward the thalamus (de Carlos and O'Leary 1992;Kageyama and Robertson 1993).…”

Fetal Exposure to Maternal Depressive Symptoms Is Associated With Cortical Thickness in Late Childhood

“…All primary sulci are formed during fetal life with development of the superior frontal, rhinal, temporal and pre- and postcentral sulci complete by 25 to 26 weeks gestation[93]. The molecular level of the human nervous system, especially in the frontal lobes, is shaped during midgestation by regressive apoptotic mechanisms[94]. Cell decline in Layer 1 during this time of enormous growth, is due to cell death in contrast to cell migration which occurs later.…”

The discovery of the subpial granular layer in the human cerebral cortex

“…The usual explanation for the gradual disappearance of the SGL is that its cells migrate inwardly into the cortical plate, thus supplementing the cortical contingent of interneurons [1,2]. However, it is worth noting that at least some of SGL cells degenerate [2] and that after 30 PCW the naturally occurring cell death is an active mechanism contributing to the disappearance of SGL cells, but not the Cajal-Retzius cells [23].…”