2020
DOI: 10.1007/s13320-020-0578-1
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Development of Rapid, Sensitive, and Effective Plasmonic Nanosensor for the Detection of Vitamins in Infact Formula and Milk Samples

Abstract: The aim of the present study is to develop a surface plasmon resonance sensor for the detection of vitamin B2, vitamin B9, and vitamin B12 in food samples by using the molecular imprinting technique. The vitamin B2, vitamin B9, and vitamin B12 imprinted and the non-imprinted surface plasmon resonance sensor chip surfaces were characterized by using contact angle measurements, atomic force microscopy, ellipsometry, and Fourier transform infrared-attenuated total reflectance. The real-time detection of vitamin B… Show more

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Cited by 34 publications
(22 citation statements)
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“…The SPR and QCM chip surfaces were cleaned with acidic piranha solution (3:1 concentrated H 2 SO 4 : H 2 O 2 , v/v), as previously reported by Çimen and Denizli (2020), Hüseynli, Çimen, Bereli, and Denizli (2019). Next, the SPR and QCM chip surfaces were carefully cleaned with ethyl alcohol and dried in a vacuum oven (200 mmHg, 40 °C) for 1 hr.…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…The SPR and QCM chip surfaces were cleaned with acidic piranha solution (3:1 concentrated H 2 SO 4 : H 2 O 2 , v/v), as previously reported by Çimen and Denizli (2020), Hüseynli, Çimen, Bereli, and Denizli (2019). Next, the SPR and QCM chip surfaces were carefully cleaned with ethyl alcohol and dried in a vacuum oven (200 mmHg, 40 °C) for 1 hr.…”
Section: Methodsmentioning
confidence: 99%
“…Both sensor techniques are easy to use, affordable, sensitive, selective, and their response time is short (Justino, Freitas, Pereira, Duarte, & Rocha, 2015; Laricchia‐Robbio & Revoltella, 2004; Piletsky & Turner, 2002). SPR and QCM sensors have been used for pharmaceutical analysis, food safety measurements, and environmental monitoring in previous studies (Bakhshpour, Özgür, Bereli, & Denizli, 2017; Çimen & Denizli, 2020; Feng, Li, Jian, Shen, & Yu, 2007; Jalilzadeh, Çimen, Özgür, Esen, & Denizli, 2019; Kartal, Çimen, Bereli, & Denizli, 2019; Saylan et al., 2017).…”
Section: Introductionmentioning
confidence: 99%
“…One of the advantages of SPR sensors is thanks to their sensitive refractive index changing during the surface binding, giving the results simultaneously and label free. SPR sensors are used in various fields for food quality control analysis [ 20 , 21 ], environmental analysis [ 22 ] and diagnostic purposes in medicine [ 23 , 24 , 25 , 26 ].…”
Section: Introductionmentioning
confidence: 99%
“…Surface plasmon polariton (SPP) is a kind of electromagnetic waves propagating along the metal-dielectric interface and has a sensitive response to the variation of RI of dielectric adjacent to the metal film [1,2]. The surface plasmon resonance (SPR) technology has now penetrated into the fields of food, biology, and environment, and demonstrated many advantages, such as high sensitivity, real-time detection, label-free, and selective recognition [3][4][5][6][7]. Due to the wavevector mismatch with optical waves, SPP waves are traditionally excited by using the Kretschmann or Otto prism based on attenuated total reflection, which has disadvantages of large volume, complex system, and high cost [8][9][10].…”
Section: Introductionmentioning
confidence: 99%
“…By optimizing the design, a better coupling between the optical guided mode and SPP mode can be achieved. In order to improve the performance of SPR sensors, many kinds of structures have been proposed, including polymer long-period waveguide grating with the liquid cladding [5], molecular imprinted based SPR sensor [7], and fiber-optic waveguide coupled SPR sensor [14]. Fan et al [15] realized ultra-thin layer sensing by using a vertical SPP-dielectric waveguide coupler, and the detection sensitivity was as high as 0.67 dB/nm.…”
Section: Introductionmentioning
confidence: 99%