Developmental Defects of the Oral and Maxillofacial Region

Neville, Brad W.; Damm, Douglas D; Allen, Carl M.; Angela, C.

doi:10.1016/b978-0-323-55225-7.00001-4

Cited by 21 publications

(38 citation statements)

References 87 publications

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“…In newborns, mucosal cysts, Bohn's nodules and Epstein pearls were the top three most common lesions (Cetinkaya et al, ; Flinck et al, ; George et al, ). This finding is aligned with current knowledge from textbooks and reports from the literature (Neville, Allen, & Chi, ). Although there were other studies that included newborns in their sample, the specific data for this age group could not be extracted .…”

Section: Discussionsupporting

confidence: 88%

World Workshop on Oral Medicine VII: Relative frequency of oral mucosal lesions in children, a scoping review

et al. 2019

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Objective To detail a scoping review on the global and regional relative frequencies of oral mucosal disorders in the children based on both clinical studies and those reported from biopsy records. Materials and Methods A literature search was completed from 1 January 1990 to 31 December 2018 using PubMed and EMBASE. Results Twenty clinical studies (sample size: 85,976) and 34 studies from biopsy services (40,522 biopsies) were included. Clinically, the most frequent conditions were aphthous ulcerations (1.82%), trauma‐associated lesions (1.33%) and herpes simplex virus (HSV)‐associated lesions (1.33%). Overall, the most commonly biopsied lesions were mucoceles (17.12%), fibrous lesions (9.06%) and pyogenic granuloma (4.87%). By WHO geographic region, the pooled relative frequencies of the most common oral lesions were similar between regions in both clinical and biopsy studies. Across regions, geographic tongue (migratory glossitis), HSV lesions, fissured tongue and trauma‐associated ulcers were the most commonly reported paediatric oral mucosal lesions in clinical studies, while mucoceles, fibrous lesions and pyogenic granuloma were the most commonly biopsied lesions. Conclusions The scoping review suggests data from the clinical studies and biopsy records shared similarities in the most commonly observed mucosal lesions in children across regions. In addition, the majority of lesions were benign in nature.

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Section: Discussionsupporting

confidence: 88%

World Workshop on Oral Medicine VII: Relative frequency of oral mucosal lesions in children, a scoping review

et al. 2019

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“…[ 1 ] Their location suggests that they may represent a failure of normal fusion of maxillary and mandibular process. [ 3 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 2 ] Commissural lip pits (CLP) are small mucosal invaginations that occur at the corner of the mouth on the vermilion border. [ 3 ] CLP can appear as unilateral depression or more frequently as bilateral depression. [ 1 3 4 ] Prevalence rates of CLP in adults range from 0.3% to 21.1%[ 4 5 6 7 8 9 10 11 ] [ Table 1 ].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of commissural lip pits in population of central Gujarat: A hospital-based study

Tailor

Joshi

2018

J Oral Maxillofac Pathol

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“…4 Ultraviolet damage is considered to be a major risk factor in this area, with considering the fact that the incidence of melanoma is increasing for populations with lighter skin as it approaches the equator. 5 There is no definitive treatment for melanoma and about 95% of melanoma cases are treated with surgery, but the rate of disease recurrence is very high. Other treatments include chemotherapy, immunotherapy, radiation therapy, and a combination of them, all have a weak effect on the cancerous tumor.…”

Section: Introductionmentioning

confidence: 99%

“…This disease develops from the accumulation of melanin seeds and spreads to the outer skin layer . Ultraviolet damage is considered to be a major risk factor in this area, with considering the fact that the incidence of melanoma is increasing for populations with lighter skin as it approaches the equator . There is no definitive treatment for melanoma and about 95% of melanoma cases are treated with surgery, but the rate of disease recurrence is very high.…”

Section: Introductionmentioning

confidence: 99%

MicroRNA‐330 inhibits growth and migration of melanoma A375 cells: In vitro study

Sehati

Sadeghie

Mansoori

et al. 2019

J of Cellular Biochemistry

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Melanoma skin cancer is one of the main causes of male cancer‐related deaths worldwide. It has been suggested that miR‐330‐5p can act as a tumor suppressor in various types of cancers. So, in this study, we replaced miR‐330 in melanoma cancer cells by vector‐based miR‐330 to evaluate the effects of this microRNA on the growth and migration inhibition of melanoma cancer cells, and to determine the molecular mechanisms underlying its action. By using the MTT assay, the IC50 of Geneticin antibiotic was obtained as 460 µg/mL. The results of the qRT‐PCR showed the increased expression level of miR‐330 and decreased expression levels of MMP‐9, CXCR4, Vimentin, melanoma cell adhesion molecule, AKT1, and E2F1 messenger RNA in A375 transfected cells. The cytotoxicity assay results demonstrated the inhibition of cancer cells proliferation. Furthermore, the wound healing test results showed a migration reduction of transfected cells with miR‐330 compared with nontransfected ones. In addition, 4′,6‐diamidino‐2‐phenylindoleLB: Luria‐Bertani (DAPI) staining revealed the significant nucleus fragmentation in miR‐330 replaced cells, which correspond to apoptosis induction in replaced cells. The results showed that increase in miR‐330 expression level could significantly inhibit the tumor cell growth and the migration of melanoma cancer cells.

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Developmental Defects of the Oral and Maxillofacial Region

Cited by 21 publications

References 87 publications

World Workshop on Oral Medicine VII: Relative frequency of oral mucosal lesions in children, a scoping review

World Workshop on Oral Medicine VII: Relative frequency of oral mucosal lesions in children, a scoping review

Prevalence of commissural lip pits in population of central Gujarat: A hospital-based study

MicroRNA‐330 inhibits growth and migration of melanoma A375 cells: In vitro study

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