Diabetes Mellitus, Obesidade E Maus Hábitos De Vida: Sua Relação Com a Covid-19

Monteiro, Amanda Rainha; Barros, Ludmila Alves dos Santos; Albernaz, Pedro Cardoso Siqueira; Vieira, Victor Barcellos de Azeredo; Barroso, Victoria Dias de Miranda Paula; Rodrigues, Marta Cristina da Cunha

doi:10.29184/1980-7813.rcfmc.377.vol.15.n2.2020

Cited by 3 publications

(3 citation statements)

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“…The association of COVID-19 to cardiopathies generates systemic inflammation due to dysregulation linked to angiotensin-converting enzyme overexpression 2 (ACE2) and elevation of cardiac injury biomarkers [ 47 , 48 ]; in addition, the virus can cause myocardial dysfunction, which aggravates the clinical condition. Among the cases of diabetes, the increase in lethality is due to the difficulty of immune response, mainly innate, due to the hyperglycemic condition, the release of cytokines and the decrease in the release of interferon, responsible for antiviral function [ 49 , 50 ]. On the other hand, cases of obesity have a worsening in the immune response, due to systemic inflammation and consequently, impairment in the performance of defense cells, in addition to coagulation factors, which can lead to the formation of thrombi [ 51 , 52 ].…”

Section: Discussionmentioning

confidence: 99%

Epidemiological Aspects of the Initial Evolution of COVID-19 in Microregion of Uberlândia, Minas Gerais (MG), Brazil

Policarpo

Lourenzatto

Brito³

et al. 2021

IJERPH

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COVID-19 is considered by the World Health Organization to be a global public health emergency, which presents regional divergences that affect the epidemiological profile of the disease and are associated with political, economic, social and behavioral aspects. We aimed to analyze the epidemiological characteristics of the disease in the microregion of Uberlândia, Brazil, in order to determine risk factors that contributed to progression of SARS-CoV-2 virus. A cross-sectional study was conducted about micro- and macro-determinants combined with the significance analysis of suspected and confirmed cases in 18 municipalities during the epidemiological weeks (EW) 9 to 26. There were 34,046 notifications, of which 4935 (14.49%) people were diagnosed with COVID-19. Of these, 282 (5.71%) required hospital care and 40 (0.81%) died. Age and presence of associated comorbidities were decisive in the variations of incidence and lethality rates. In general, young people were the most affected and the elderly people, the most exposed to the serious and lethal form (p < 0.0001). Comorbidities such as diabetes and cardiopathies increased 33.5 times the death risk. The dispersion of the virus was centrifugal, in the inter as well as in the intra-municipal level. The disorderly implementation of municipal decrees applied in a decentralized manner in the municipalities seems to have contributed for the incidence rates increasing in the EW 25 and 26.

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Section: Discussionmentioning

confidence: 99%

Epidemiological Aspects of the Initial Evolution of COVID-19 in Microregion of Uberlândia, Minas Gerais (MG), Brazil

Policarpo

Lourenzatto

Brito³

et al. 2021

IJERPH

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“…Studies show that people with previous comorbidities increase the chance of infection and there is a greater probability of death from the disease compared to people who have no pre-existing conditions (10,11) . The most relevant comorbidities are: arterial hypertension, cardiovascular diseases, diabetes and respiratory illnesses, which were considered risk factors for fatality, as these diseases share characteristics with infectious diseases, such as the pro-inflammatory state, attenuation of the innate component of the immune response and low immune function, by affecting macrophages and lymphocyte function, which can make individuals more prone to disease complications (12) .…”

Section: Discussionmentioning

confidence: 99%

Anxiety and depression in patients with post-COVID-19 comorbities

R. da Rocha,

T. N. D. Rodrigues,

C. Santos

et al. 2024

mtprehabjournal

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Background: The COVID-19 pandemic has brought significant impacts on mental health, increasing conditions such as anxiety and depression. The negative impact was even bigger among the population with chronic illnesses like diabetes, hypertension, and obesity. Fear of contamination, social isolation, lack of medical follow-up, and changes in lifestyle have contributed to the worsening of these disorders. Objective: The aim of this study was to assess anxiety and depression levels and quality of life in individuals with pre-existing comorbidities post COVID-19. Methods: This is a cross-sectional study with a descriptive and analytical approach. The study included 125 individuals divided in healthy group and chronically ill group. Behavioral and clinical characteristics were evaluated, such as physical activity after COVID-19, smoking, alcohol consumption, pre-existing comorbidities, and symptoms of anxiety and depression. Results: The study highlighted that the patients with diabetes and hypertension suffered the most from anxiety and depression possibly due to the higher susceptibility to coronavirus infection and the negative impact of these pre-existing conditions on mental health. In hypertensive individuals, the complex interaction between emotional stress, anxiety, and cardiovascular system dysregulation contributed to increased levels of anxiety and depression. Obesity, besides a risk factor for severe COVID-19, it also negatively impacted the immune system and had adverse effects on mental health, with an increase in depressive and anxious symptoms. Conclusion: This study emphasizes the need of special care to at-risk groups to minimize adverse impacts on mental health and improve the quality of life of individuals with pre-existing comorbidities post COVID-19.

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“…These conditions may even be present in current cases of acute respiratory syndrome, caused by the SARSCoV-2 virus (Coronavirus 2 of severe acute respiratory syndrome), which causes COVID-19 (Coronavirus Disease 19) 10 , that is a current concern. increasing and already affects 10.5% of the global population, however 44.7% are not diagnosed and, this year, the number of deaths reached 6.7 million people 11 .…”

Section: Introductionmentioning

confidence: 99%

Astaxanthin supplementation extracted from Haematococcus pluvialis on clinical parameters associated with chronic diseases and metabolic syndrome / Suplementação de astaxantina extraída de Haematococcus pluvialis sobre os parâmetros clínicos associados com doenças crônicas e síndrome metabólica

Altoé¹,

Paes²,

Cirino³

et al. 2022

BJDV

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Introduction: astaxanthin is a carotenoid compound found in marine organisms that, according to several studies, has significantly increased antioxidant properties, with possible benefits for the prevention and treatment of chronic diseases and metabolic syndrome. Objective: to indicate the possible biological effects of astaxanthin, as well as its forms of prescription and possible benefits for the prevention and treatment of chronic diseases and metabolic syndrome. Method: integrative review of clinical experimental studies, mainly, but of some pre-clinical studies, also published since 2000. The searches were carried out in the following databases: Pubmed, SciELO and Semantic Scholar. Results: the results indicated doses between 0.5 and 21.6mg/day, for a period from 2 weeks to 12 months, involving volunteers aged between 8 and 85 years, both genders. Supplements with astaxanthin indicated the ability to reduce oxidative stress, as well as biochemical parameters in the blood, such as low-density lipoprotein, total cholesterol, fasting glucose, triglycerides, glycated hemoglobin and others. The bioactive substance is also associated with a reduction in blood pressure, increased blood operations of high-density lipoprotein and adiponectin, reinforcing the hypothesis that astaxanthin is promising, as an aid in the prevention and treatment of chronic diseases and metabolic syndrome. Conclusion: astaxanthin appears to be a complementary and innovative element for the prevention and treatment of chronic diseases and metabolic syndrome. However, no supplement will have a “miraculous” effect and will replace with constant changes in lifestyle, including healthy eating. The antioxidant effects of astaxanthin were confirmed and associated with the most varied metabolic and clinical outcomes. However, due to the reduced amount of evidence and heterogeneity of variables, further research is needed.

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Diabetes Mellitus, Obesidade E Maus Hábitos De Vida: Sua Relação Com a Covid-19

Cited by 3 publications

References 1 publication

Epidemiological Aspects of the Initial Evolution of COVID-19 in Microregion of Uberlândia, Minas Gerais (MG), Brazil

Epidemiological Aspects of the Initial Evolution of COVID-19 in Microregion of Uberlândia, Minas Gerais (MG), Brazil

Anxiety and depression in patients with post-COVID-19 comorbities

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