Diagnosis in Otorhinolaryngology

Önerci, T. Metin; Altunay, Zeynep Onerci

doi:10.1007/978-3-030-64038-5

Cited by 4 publications

(2 citation statements)

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“…However, bacterial rhinosinusitis can develop following viral rhinosinusitis in approximately 0.5-2% of viral illnesses. Only 60% of clinically diagnosed bacterial rhinosinusitis cases have shown positive results in culture samples [14,15].…”

Section: Discussionmentioning

confidence: 99%

Mucolytic and Antioxidant Effects of Intranasal Acetylcysteine Use on Acute Rhinosinusitis in Rats with an Acute Rhinosinusitis Model

Savran

Karabulut

Yılmaz

et al. 2022

ORL

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Introduction: The aim of this study was to investigate whether N-acetylcysteine (NAC) is effective in the treatment murine model of acute rhinosinusitis in rats. Materials and Methods: Twelve rats were included in the study. The left nasal cavity of all rats was infected with Streptococcus pneumoniae. Group 1 was the group in which NAC was administered into the left nasal cavity twice daily. Group 2 was selected as the control group. All rats were then sterilely sacrificed under anesthesia after intracardiac blood sampling. After sacrifice, sterile culture samples were collected from the posterior nasal cavity. Results: Total oxidant status and oxidative stress index (OSI), interleukin 1β, interleukin 6, and tumor necrosis factor α levels decreased significantly in the treatment group. Total antioxidant status was significantly increased. There was a statistically significant increase in total serum thiol levels and native thiol levels. Histopathologic evaluation showed a statistically significant decrease in submucosal gland hypertrophy in the treatment group. Conclusion: According to our study, intranasal application of NAC can decrease the inflammatory findings in murine acute rhinosinusitis.

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Section: Discussionmentioning

confidence: 99%

Mucolytic and Antioxidant Effects of Intranasal Acetylcysteine Use on Acute Rhinosinusitis in Rats with an Acute Rhinosinusitis Model

Savran

Karabulut

Yılmaz

et al. 2022

ORL

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“…It is known that such anatomical variations may cause chronic rhinosinusitis by narrowing the nasal passage and ostiomeatal complex. Agger nasi cell, concha bullosa, septum deviation, hyperpneumatized ethmoid bulla, Haller cell, paradox middle concha and pneumatized uncinate process can be listed among the most frequently detected anatomical variations using computed tomography (4,5).…”

Section: Introductionmentioning

confidence: 99%

The effect of paranasal anatomic variations on chronic rhinosinusitis

TANYERİ¹,

ÇELEBİ²,

Mehel³

2022

JECM

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Rhinosinusitis is the inflammation of the paranasal sinus mucosa and the most common pathophysiological event causing rhinosinusitis is the ostiomeatal complex disease. The aim of the study is to determine the prevalence of anatomical variations and mucosal pathologies in paranasal computed tomography images of patients with chronic rhinosinusitis and to reveal the relationship between anatomical variations and sinus pathologies. Anatomical variations and mucosal pathologies in coronal paranasal tomography images were evaluated in 100 patients diagnosed with chronic rhinosinusitis and 32 individuals in the control group without any sinus complaints. The rate of having at least one anatomical variation in the control group was 64.1%, while this rate was 87.5% in patients with chronic rhinosinusitis (p<0.001). The most common variation, Agger nasi cell, was found to be present in 34.3% of the individuals in the control group and in 53.5% in the rhinosinusitis group (p<0.05). In patients with rhinosinusitis, maxillary sinus was affected in 66.5%, anterior ethmoid sinus in 42.5%, frontal sinus in 32.5%, posterior ethmoid sinus in 20%, sphenoid sinus in 18.5% either in isolation or in combination. The relationship between anatomical variations and mucosal pathologies of the sinuses was evaluated. A significant correlation was found between anatomical variations such as Agger nasi cell, concha bullosa, septum deviation, ethmoid bulla and Haller cell with maxillary sinusitis, between Agger nasi cell and septum deviation with frontal sinusitis, and between Agger nasi cell, concha bullosa, septum deviation and ethmoid bulla with ethmoid sinusitis. In conclusion; it was concluded that anatomical variations are an important factor in the development of chronic sinusitis and that not only sinuses but also anatomical variations that impair drainage should be corrected during the surgical treatment of rhinosinusitis.

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Dynamical analysis of a fractional discrete-time vocal system

Vignesh

Banerjee

2022

Nonlinear Dyn

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Diagnosis in Otorhinolaryngology

Cited by 4 publications

References 0 publications

Mucolytic and Antioxidant Effects of Intranasal Acetylcysteine Use on Acute Rhinosinusitis in Rats with an Acute Rhinosinusitis Model

Mucolytic and Antioxidant Effects of Intranasal Acetylcysteine Use on Acute Rhinosinusitis in Rats with an Acute Rhinosinusitis Model

The effect of paranasal anatomic variations on chronic rhinosinusitis

Dynamical analysis of a fractional discrete-time vocal system

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