Diagnosis of <i>Helicobacter pylori</i> Infection

Makristathis, Athanasios; Hirschl, Alexander M.; Lehours, Philippe; Mégraud, Françis

doi:10.1111/j.1083-4389.2004.00254.x

Cited by 42 publications

(28 citation statements)

References 70 publications

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“…The sensitivity of stool antigen test in simple ulcer as reported in literature is in range of 88-100%. 17 However, no report is available on utilization of stool antigen test for detection H. pylori in complicated ulcer disease specially in postoperative setting.…”

Section: Resultsmentioning

confidence: 99%

The prevalence of Helicobacter pylori in perforated peptic ulcer disease

Rehmani

Pathak

2018

Int Surg J

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Background: Although the role of Helicobacter pylori infection in noncomplicated peptic ulcer disease has been definitively established, the precise relationship between the organism and ulcer complications is doubtful. Recurrent ulcer disease after peptic ulcer perforation mainly occurs in patients with H. pylori infection, which suggests that the microorganism plays an important role in this complication.Methods: This observational study was conducted in the Department of General Surgery, Himalayan Institute of Medical Sciences (HIMS), Swami Ram Nagar, Dehradun, over a period of January 2013 to December 2013 and included 75 subjects who underwent exploratory laparotomy for peptic ulcer perforation. The tests used for the diagnosis of H. pylori are mucosal biopsy at the time of surgery, Rapid urease test (RUT), Stool antigen test.Results: In this study, H. pylori infection was found to be present in 61% of these patients as detected by biopsy. There were 66 males and 9 females. Infection with H. pylori is almost universal in patients aged more than 70 years.Conclusions: In the Indian context patients presenting with perforation should be tested for infection with H. pylori utilizing a gastric antral mucosal biopsy taken at the time of operation for histological analysis and eradication therapy should be advised to all those who are found positive.

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Section: Resultsmentioning

confidence: 99%

The prevalence of Helicobacter pylori in perforated peptic ulcer disease

Rehmani

Pathak

2018

Int Surg J

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“…In addition to identifying infection, it permits testing for sensitivity to anti-microbial agents. 239 However, bacterial culture is relatively insensitive 240,241 and seldom performed in routine clinical practise. Not all hospital laboratories have necessary expertise or resources available to offer routine culturing.…”

Section: Culturementioning

confidence: 99%

Helicobacter Pylori Infection in Peptic Ulcer Disease

Tsang¹,

Shrestha²

2011

Peptic Ulcer Disease

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“…Serological tests are widely used [13] but they cannot differentiate a current infection from a past exposure [10] . Performance of serological tests depends on the antigen preparation used [12,14] , and as H pylori strains differ among geographic locations, local validation of the test is necessary [13,14] . [15][16][17][18][19][20] .…”

Section: Wwwwjgnetcommentioning

confidence: 99%